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Phosphatidylinositol-Binding Clathrin Assembly Protein

Known as: Clathrin Assembly Lymphoid Myeloid Leukemia Protein, PICALM 
Phosphatidylinositol-binding clathrin assembly protein (652 aa, ~70 kDa) is encoded by the human PICALM gene. This protein plays a role in endosomal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
PICALM, a clathrin adaptor protein, plays important roles in clathrin-mediated endocytosis in all cell types. Recently, genome… Expand
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Highly Cited
2013
Highly Cited
2013
Significance β-Amyloid aggregates are often found in the brains of Alzheimer’s patients. We have previously reported that… Expand
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Highly Cited
2012
Highly Cited
2012
One of the pathological hallmarks of Alzheimer disease is the accumulation of amyloid plaques in the extracellular space in the… Expand
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Highly Cited
2011
Highly Cited
2011
SNAREs provide a large part of the specificity and energy needed for membrane fusion and, to do so, must be localized to their… Expand
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Highly Cited
2011
Highly Cited
2011
CONTEXT Two recent and simultaneously published genome-wide association studies independently implicated clusterin (CLU… Expand
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Highly Cited
2006
Highly Cited
2006
Receptor-mediated endocytosis of ligands, such as transferrin and LDL, is suppressed when clathrin synthesis is blocked by RNA… Expand
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Highly Cited
2005
Highly Cited
2005
The endocytic accessory clathrin assembly lymphoid myeloid leukemia protein (CALM) is the ubiquitously expressed homolog of the… Expand
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Highly Cited
2003
Highly Cited
2003
To assess the contribution of individual endocytic proteins to the assembly of clathrin coated pits, we depleted the clathrin… Expand
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2003
2003
Recessive N-ethyl-N-nitrosourea (ENU)-induced mutations recovered at the fitness-1 (fit1) locus in mouse chromosome 7 cause… Expand
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Highly Cited
2001
Highly Cited
2001
Adaptor protein 180 (AP180) and its homolog, clathrin assembly lymphoid myeloid leukemia protein (CALM), are closely related… Expand
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