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PHLPP2 gene

Known as: KIAA0931, PH DOMAIN AND LEUCINE-RICH REPEAT PROTEIN PHOSPHATASE-LIKE, PHLPP-LIKE 
This gene is involved in the regulation of apoptosis.
National Institutes of Health

Papers overview

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2017
2017
The PI3K-Akt pathway is one of the most commonly dysregulated cancer-associated signaling pathways. Here we report an oncogenic… Expand
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2015
2015
BackgroundBladder cancer is the most common malignancy in urinary system and the ninth most common malignancy in the world… Expand
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2015
2015
UNLABELLED We have recently recapitulated metastasis of human PTEN/TP53-mutant prostate cancer in the mouse using the RapidCaP… Expand
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2015
2015
Acetaminophen (APAP) is frequently taken to relieve pain. Staggered APAP overdoses have been reported to cause acetaminophen… Expand
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2015
2015
Purpose: The carcinogenic capacity of B[a]P/B[a]PDE is supported by epidemiologic studies. However, the molecular mechanisms… Expand
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2014
2014
The dysregulation of microRNAs (miRNAs) is crucially implicated in the development of various cancers. In this study, we explored… Expand
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Highly Cited
2013
Highly Cited
2013
Purpose: To investigate the clinicopathologic significance, role, and mechanism of action of microRNA-224 (miR-224) in colorectal… Expand
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Highly Cited
2013
Highly Cited
2013
AKT signaling is constitutively activated in various cancers, due in large part to loss-of-function in the PTEN and PHLPP… Expand
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Highly Cited
2011
Highly Cited
2011
Hyperactivation of the PI 3-kinase/AKT pathway is a driving force of many cancers. Here we identify the AKT-inactivating… Expand
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Highly Cited
2007
Highly Cited
2007
Akt/protein kinase B controls cell growth, proliferation, and survival. We recently discovered a novel phosphatase PHLPP, for PH… Expand
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