PHLPP2 gene

Known as: KIAA0931, PH DOMAIN AND LEUCINE-RICH REPEAT PROTEIN PHOSPHATASE-LIKE, PHLPP-LIKE 
This gene is involved in the regulation of apoptosis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
051020072017

Papers overview

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2015
2015
Bladder cancer is the most common malignancy in urinary system and the ninth most common malignancy in the world. MicroRNAs… (More)
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2015
2015
UNLABELLED We have recently recapitulated metastasis of human PTEN/TP53-mutant prostate cancer in the mouse using the RapidCaP… (More)
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2015
2015
MicroRNAs are known to be involved in carcinogenesis and tumor progression in glioma. Recently, microRNA-372 (miR-372) has been… (More)
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2014
2014
The dysregulation of microRNAs (miRNAs) is crucially implicated in the development of various cancers. In this study, we explored… (More)
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2014
2014
The androgen receptor (AR) is a transcription factor involved in prostate cell growth, homeostasis and transformation regulated… (More)
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2013
2013
AKT signaling is constitutively activated in various cancers, due in large part to loss-of-function in the PTEN and PHLPP… (More)
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2013
2013
PURPOSE To investigate the clinicopathologic significance, role, and mechanism of action of microRNA-224 (miR-224) in colorectal… (More)
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2010
2010
PH domain Leucine-rich repeat protein phosphatase (PHLPP) directly dephosphorylates and inactivates Akt and protein kinase C… (More)
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2009
2009
PHLPP2 (PH domain leucine-rich repeat protein phosphatase 2) terminates Akt and protein kinase C (PKC) activity by specifically… (More)
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Highly Cited
2007
Highly Cited
2007
Akt/protein kinase B controls cell growth, proliferation, and survival. We recently discovered a novel phosphatase PHLPP, for PH… (More)
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