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Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.
Familial adenomatous polyposis coli (FAP) is a disease characterized by the development of multiple colorectal adenomas, and affected individuals carry germline mutations in the APC gene. With theExpand
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Chromatographic analysis of tetracycline antibiotics in foods.
Tetracycline antibiotics (TCs), such as oxytetracycline, tetracycline, chlortetracycline, and doxycycline, have for decades continued to play an important role in veterinary medicine and feedExpand
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Improving the solubility and pharmacological efficacy of curcumin by heat treatment.
Lipid peroxidation has been implicated in a variety of diseases. 4-Hydroxy-2-nonenal (HNE), a major oxidation by-product, is cytotoxic, mutagenic, and genotoxic, being involved in diseaseExpand
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The fourth arginine catabolic pathway of Pseudomonas aeruginosa.
D-Arginine dehydrogenase activity was discovered in Pseudomonas aeruginosa. This enzyme was inducible by its substrate, D-arginine, as well as by its product, 2-ketoarginine, but not by L-arginine.Expand
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Detection and identification of metabolites of microcystins formed in vivo in mouse and rat livers.
The hepatic metabolism of microcystins (MCs), potent cyclic peptide hepatotoxins produced by cyanobacteria, was studied by i.p. injection in mice and rats. An immunoaffinity purification method usingExpand
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Molecular cloning of adipocyte-derived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase.
In the current study, we report the cloning and initial characterization of a novel human cytosolic aminopeptidase named adipocyte-derived leucine aminopeptidase (A-LAP). The sequence encodes aExpand
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Dextran Sodium Sulfate Inhibition of Real‐Time Polymerase Chain Reaction Amplification: A Poly‐A Purification Solution
Background: Dextran sulfate sodium (DSS) induces experimental colitis and promotes colitis‐associated cancer in rodents. Here we document potent inhibition of real‐time quantitative polymerase chainExpand
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A 49-kilodalton phosphoprotein in the Drosophila photoreceptor is an arrestin homolog.
The gene encoding the 49-kilodalton protein that undergoes light-induced phosphorylation in the Drosophila photoreceptor has been isolated and characterized. The encoded protein has 401 amino acidExpand
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One of the endothelin gene family, endothelin 3 gene, is expressed in the placenta
A cDNA encoding human endothelin 3 (ET‐3) precursor was cloned from a cDNA library from the placenta, and its nucleotide and deduced amino acid sequences were determined. This ET‐3 cDNA was found toExpand
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Drosocrystallin, a major 52 kDa glycoprotein of the Drosophila melanogaster corneal lens. Purification, biochemical characterization, and subcellular localization.
We have identified a 52 kDa protein, which is a potent substrate for cholera toxin-dependent ADP-ribosylation, in the compound eye preparation of the fruit fly, Drosophila melanogaster. We find thatExpand
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