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PHLPP1 wt Allele

Known as: PLEKHE1, SCOP, PHLPP 
Human PHLPP1 wild-type allele is located in the vicinity of 18q21.32 and is approximately 265 kb in length. This allele, which encodes PH domain… 
National Institutes of Health

Related topics

Related topics

7 relations
18q21.32DephosphorylationHydrolysisProtein dephosphorylation

Broader (1)

PHLPP1 gene

Papers overview

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2015
2015
Low expression of PHLPP1 in sacral chordoma and its association with poor prognosis.
Sacral chordoma is a rare spine tumor with a high recurrence rate even after optimal therapy. Previous studies have demonstrated… 
2013
2013
Pharmacological Inhibition of Pleckstrin Homology Domain Leucine-Rich Repeat Protein Phosphatase Is Neuroprotective: Differential Effects on Astrocytes
Pleckstrin homology domain and leucine-rich repeat protein phosphatase 1 (PHLPP1) inhibits protein kinase B (AKT) survival… 
2010
2010
PHLPP1 splice variants differentially regulate AKT and PKCα signaling in hippocampal neurons: characterization of PHLPP proteins in the adult hippocampus
J. Neurochem. (2010) 115, 941–955. 
2010
2010
Serine/threonine kinase akt activation regulates the activity of retinal serine/threonine phosphatases, PHLPP and PHLPPL
J. Neurochem. (2010) 113, 477–488. 
2008
2008
Mitochondrial PINK1—A Novel Cardioprotective Kinase?
1995
1995
The behavioral effects of MK-801 injected into nucleus accumbens and caudate-putamen of rats
1994
1994
Effects of (R)-α-methylhistamine and scopolamine on spatial learning in the rat assessed using a water maze
The effects of (R)-α-methylhistamine ((R)-α-MeHA, a selective H3-receptor agonist) and scopolamine (SCOP, a muscarinic antagonist… 
Highly Cited
1992
Highly Cited
1992
Effects of physostigmine and scopolamine on rats' performances in object-recognition and radial-maze tests
The effects of physostigmine and scopolamine were evaluated on working memory of rats in object recognition and radial-maze tests… 
1992
1992
Circadian effects of scopolamine on memory, exploratory behavior, and muscarinic receptors in mouse brain.
Mice were maintained at light-dark cycle with lights on from 05:00-19:00 for 10 d in laboratory. The study was performed at 07:00… 
1991
1991
Dose-dependent effects of scopolamine on nocturnal growth hormone secretion in normal adult men : relation to δ-sleep changes
To explore the sensitivity of nocturnal GH secretion to different degrees of cholinergic blockade, we investigated the effects of… 
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