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Decreased cortisol levels in adolescent girls with conduct disorder.
Morning plasma cortisol levels were significantly diminished in adolescent girls with CD, and appear to be most strongly associated with antisocial girls who do not have other psychiatric disorders. Expand
Environmental enrichment lowers stress-responsive hormones in singly housed male and female rats
Interaction with the Kong Toys and Nestlets appears to have provided the rats with a diversion from monotonous cage life, resulting in lower HPA axis activity before and after mild stress. Expand
A role for cell sex in stem cell–mediated skeletal muscle regeneration: female cells have higher muscle regeneration efficiency
It is shown here that cell sex is a variable that considerably influences MDSCs' regeneration abilities and should persuade researchers to report cell sex, which is a largely unexplored variable, and consider the implications of relying on cells of one sex. Expand
Adrenal gland volume in major depression. Increase during the depressive episode and decrease with successful treatment.
Adrenal gland enlargement occurring during an episode of major depression appears to be state-dependent, in that it reverts to the normal size range during remission after treatment, and it thus does not appear to be an index of cumulative lifetime depression. Expand
Issues for DSM-5: whither melancholia? The case for its classification as a distinct mood disorder.
Melancholia, a syndrome with a long history and distinctly specific psychopathological features, is inadequately differentiated from major depression by the DSM-IV specifier, and it deserves recognition as a separate identifiable mood disorder. Expand
Detection and Management of Cognitive Impairment in Primary Care: The Steel Valley Seniors Survey
Characteristics of older primary care patients who were cognitively impaired and who underwent mental status testing by their physicians are identified. Expand
Neuroendocrine aspects of primary endogenous depression. I. Cortisol secretory dynamics in patients and matched controls.
The cortisol measures before and after dexamethasone administration were positively correlated to a similar degree in the patients and their controls, suggesting that predexamethAsone hypothalamic-pituitary-adrenocortical hyperactivity and postdexamETHasone cortisol nonsuppression are not independently determined in endogenous depression. Expand
Adrenal androgen and gonadal hormone levels in adolescent girls with conduct disorder
The data suggest that girls with CD, particularly aggressive CD, have lower cortisol to DHEA ratios, higher levels of free testosterone, and lower levels of sex hormone binding globulin (SHBG). Expand
Regional xenon 133 cerebral blood flow and cerebral technetium 99m HMPAO uptake in unmedicated patients with obsessive-compulsive disorder and matched normal control subjects. Determination by
We measured regional cerebral blood flow (rCBF) with the xenon 133 (133Xe) inhalation method and with regional cerebral uptake of technetium 99m d,l-hexamethyl propyleneamine oxime (99mTc-HMPAO) byExpand
Alprazolam in panic disorder and agoraphobia: results from a multicenter trial. II. Patient acceptance, side effects, and safety.
Treatment-related side effects that were worse in patients taking alprazolam than in those taking placebo included sedation, fatigue, ataxia, slurred speech, and amnesia, which tended to subside with dose reduction or continued administration of the drug. Expand