PHGDH gene

Known as: Phosphoglycerate Dehydrogenase Gene, PHOSPHOGLYCERATE DEHYDROGENASE, 3PGDH 
This gene plays a role in amino acid synthesis.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2017
010203019682017

Papers overview

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2016
2016
Serine is both a proteinogenic amino acid and the source of one-carbon units essential for de novo purine and deoxythymidine… (More)
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2015
2015
Human d-3-phosphoglycerate dehydrogenase (PHGDH), the first enzyme in the serine biosynthetic pathway, is genomically amplified… (More)
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Highly Cited
2011
Highly Cited
2011
Cancer cells adapt their metabolic processes to drive macromolecular biosynthesis for rapid cell growth and proliferation. RNA… (More)
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Highly Cited
2011
Highly Cited
2011
Most tumors exhibit increased glucose metabolism to lactate, however, the extent to which glucose-derived metabolic fluxes are… (More)
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2009
2009
In all applications of clone detection it is important to have precise and efficient clone identification algorithms. This paper… (More)
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2005
Highly Cited
2005
To investigate defensin gene copy number polymorphisms, a quantitative real-time PCR assay was developed and used to study DNA… (More)
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2003
2003
Nonessential amino acid L-Ser plays an essential role in neuronal survival and differentiation, through preferential expression… (More)
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2001
2001
l-Serine is synthesized from glycolytic intermediate 3-phosphoglycerate and is an indispensable precursor for the synthesis of… (More)
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2001
2001
We derive a Stokes parameter model to calculate the penalties due to the combination of polarization mode dispersion (PMD… (More)
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