Phosphoglycerate dehydrogenase

Known as: Dehydrogenase, Phosphoglycerate, Oxidoreductase, Phosphoglycerate, Dehydrogenase, D-3-Phosphoglycerate 
An enzyme that catalyzes the oxidation of 3-phosphoglycerate to 3-phosphohydroxypyruvate. It takes part in the L-SERINE biosynthesis pathway.
National Institutes of Health

Papers overview

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2014
2014
Human d-3-phosphoglycerate dehydrogenase (PHGDH), the first enzyme in the serine biosynthetic pathway, is genomically amplified… (More)
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2008
2008
The crystal structure of Mycobacterium tuberculosis d-3-phosphoglycerate dehydrogenase has been solved with bound effector, l… (More)
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2004
2004
Phosphoglycerate dehydrogenase (PGDH) catalyzes the first step in the serine biosynthetic pathway. In lower plants and bacteria… (More)
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Highly Cited
2003
Highly Cited
2003
Several microbial pathogens augment their invasive potential by binding and activating human plasminogen to generate the… (More)
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2001
Highly Cited
2001
A novel ligand-binding domain, named the 'ACT domain', was recently identified by a PSI-BLAST search. The archetypical ACT domain… (More)
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Highly Cited
2000
Highly Cited
2000
Unlike normal mammalian cells, which use oxygen to generate energy, cancer cells rely on glycolysis for energy and are therefore… (More)
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2000
2000
3-phosphoglycerate dehydrogenase (PHGDH) deficiency is a disorder of L-serine biosynthesis that is characterized by congenital… (More)
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1996
1996
Escherichia coli D-3-phosphoglycerate dehydrogenase (ePGDH) is a tetramer of identical subunits that is allosterically inhibited… (More)
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1977
1977
The catalytic mechanism of the phosphoglycerate dehydrogenase reaction in both directions was investigated by studying: (a) pre… (More)
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1975
1975
3-Phosphoglycerate dehydrogenase (3-phosphoglycerate:NAD oxidoreductase, EC. 1.1.1.95) was purified from Bacillus subtilis by… (More)
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