The structure of vitellogenin provides a molecular model for the assembly and secretion of atherogenic lipoproteins.
It is shown that the globular amino-terminal regions of apoB and MTP are closely related in structure to the ancient egg yolk storage protein, vitellogenin (VTG).
POCKET: a computer graphics method for identifying and displaying protein cavities and their surrounding amino acids.
The allosteric ligand site in the Vmax-type cooperative enzyme phosphoglycerate dehydrogenase
The crystal structure of the phosphoglycerate dehydrogenase from Eschehchia coli is unique among dehydrogenases and may play a key role in both catalysis and allosteric inhibition.
The Crystal Structure of the Liver Fatty Acid-binding Protein
- James Thompson, N. Winter, D. Terwey, J. Bratt, L. Banaszak
- ChemistryJournal of Biological Chemistry
- 14 March 1997
The crystal structure of the recombinant form of rat liver fatty acid-binding protein was completed to 2.3 Å and refined to an R factor of 19.0%. The structural solution was obtained by molecular…
Lipid-binding proteins: a family of fatty acid and retinoid transport proteins.
The structural basis of lipid interactions in lipovitellin, a soluble lipoprotein.
Crystal structure of rat intestinal fatty-acid-binding protein. Refinement and analysis of the Escherichia coli-derived protein with bound palmitate.
Intracellular lipid-binding proteins and their genes.
Intracellular lipid-binding proteins are a family of low-molecular-weight single-chain polypeptides that form 1:1 complexes with fatty acids, retinoids, or other hydrophobic ligands. These proteins…
Sequestration of the active site by interdomain shifting. Crystallographic and spectroscopic evidence for distinct conformations of L-3-hydroxyacyl-CoA dehydrogenase.
- J. Barycki, L. O'Brien, A. Strauss, L. Banaszak
- Chemistry, BiologyJournal of Biological Chemistry
- 1 September 2000
A novel charge transfer complex has been identified in the course of abortive ternary complex formation, and its characterization provides additional insight into aspects of the catalytic mechanism of l-3-hydroxyacyl-CoA dehydrogenase.
Lipid-protein interactions in lipovitellin.
The refined molecular structure of lipovitellin is described using synchrotron cryocrystallographic data to 1.9 A resolution to provide insights into the factors governing lipoprotein formation.