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The detection of anthelmintic resistance in nematodes of veterinary importance.
Drug resistance in veterinary helminths.
- R. Prichard
- MedicineVeterinary parasitology
Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog.
Moxidectin and the avermectins: Consanguinity but not identity.
The kinetics of triclabendazole disposition in sheep.
- D. Hennessy, E. Lacey, J. W. Steel, R. Prichard
- Chemistry, BiologyJournal of veterinary pharmacology and…
- 1 March 1987
To investigate whether the disposition of triclabendazole (TCBZ) and its metabolites in blood or bile influenced its flukicidal potency, TCBZ was administered intraruminally at 10 mg kg-1 to sheep…
Genetic variability following selection of Haemonchus contortus with anthelmintics.
- R. Prichard
- Biology, MedicineTrends in Parasitology
- 1 September 2001
Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two-phase epidemiological study
Mutations in the extracellular domains of glutamate‐gated chloride channel α3 and β subunits from ivermectin‐resistant Cooperia oncophora affect agonist sensitivity
- A. Njue, Jon Hayashi, L. Kinne, Xiao-Peng Feng, R. Prichard
- BiologyJournal of Neurochemistry
- 1 June 2004
Electrophysiological whole‐cell voltage‐clamp recordings showed that mutations in the IVR GLUClα3 caused a modest but significant threefold loss of sensitivity to glutamate, the natural ligand for GluCl receptors, and a significant decrease in sensitivity to the anthelmintics ivermectin and moxidectin was observed in theIVR Gluclα3 receptor.