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PHGDH wt Allele

Known as: SERA, Phosphoglycerate Dehydrogenase wt Allele, PGD 
Human PHGDH wild-type allele is located in the vicinity of 1p12 and is approximately 84 kb in length. This allele, which encodes D-3-phosphoglycerate… 
National Institutes of Health

Related topics

Related topics

8 relations
Amino Acid BiosynthesisD-3-Phosphoglycerate Dehydrogenase, humanGlycine, Serine and Threonine Metabolism PathwayOxidation-Reduction

Broader (1)

PHGDH gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Preconception omega-3 fatty acid supplementation of adult male mice with a history of developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure prevents preterm birth in unexposed female partners.
We have recently reported that adult male C57BL/6 mice exposed in utero to the environmental toxicant 2,3,7,8-tetrachlorodibenzo… 
2008
2008
15‐hydroxyprostaglandin dehydrogenase suppresses K‐RasV12‐dependent tumor formation in Nu/Nu mice
Oncogenic Ras mutations are early genetic events in colorectal cancer that induce cyclooxygenase (COX)‐2 expression and… 
2002
2002
Cortisol/progesterone antagonism in regulation of 15-hydroxysteroid dehydrogenase activity and mRNA levels in human chorion and placental trophoblast cells at term.
PGs mediate parturition events. 15-Hydroxyprostaglandin dehydrogenase (PGDH) catalyzes the first step in the metabolism of PGs to… 
1999
1999
The Contribution of Adjacent Subunits to the Active Sites ofd-3-Phosphoglycerate Dehydrogenase*
d-3-Phosphoglycerate dehydrogenase (PGDH) from Escherichia coli is allosterically inhibited by l-serine, the end product of its… 
Highly Cited
1997
Highly Cited
1997
15-hydroxyprostaglandin dehydrogenase: implications in preterm labor with and without ascending infection.
There is evidence that intrauterine infection, which stimulates PG synthesis may play a role in the pathogenesis of some preterm… 
1988
1988
Human placental 15-hydroxy-prostaglandin dehydrogenase activity is under fetal genetic control.
Review
1983
Review
1983
Inhibition of prostaglandin 15-hydroxydehydrogenase by sulphasalazine and a novel series of potent analogues.
Review
1977
Review
1977
Enzymes in renal diseases.
Recent progress is reviewed in the diagnostic enzymology of renal dis­ eases. Enzyme determinations in blood serum are of little… 
1974
1974
Purification of the human placental 15 hydroxy prostaglandin dehydrogenase: Properties of the purified enzyme
1959
1959
Comparative studies on D-glyceraldehyde-3-phosphate dehydrogenase. VII. Studies on the digestibility of the enzyme isolated from various mammals.
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