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PDE3A gene

Known as: PHOSPHODIESTERASE 3A, cGMP-INHIBITED, phosphodiesterase 3A, cAMP PHOSPHODIESTERASE, MYOCARDIAL cGMP-INHIBITED 
National Institutes of Health

Related topics

Related topics

2 relations
Cyclic Nucleotide Phosphodiesterases, Type 3Cyclic Nucleotide Phosphodiesterases, Type 3A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Modulation of Polycystic Kidney Disease Severity by Phosphodiesterase 1 and 3 Subfamilies.
Aberrant intracellular calcium levels and increased cAMP signaling contribute to the development of polycystic kidney disease… 
2010
2010
Carbon-11 labeled papaverine as a PET tracer for imaging PDE10A: radiosynthesis, in vitro and in vivo evaluation.
2009
2009
Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity
ADP-ribosylation factors (ARFs) have crucial roles in vesicular trafficking. Brefeldin A-inhibited guanine nucleotide-exchange… 
Highly Cited
2008
Highly Cited
2008
Generation of mouse oocytes defective in cAMP synthesis and degradation: endogenous cyclic AMP is essential for meiotic arrest.
2007
2007
NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase inhibitor, improves reduced walking distance and lowered hindlimb plantar surface temperature in a rat experimental…
2001
2001
Phosphodiesterase 3 as a potential target for therapy of malignant tumors in the submandibular gland
Phosphodiesterase (PDE) 3s have been characterized in human neoplastic submandibular gland intercalated duct HSG cells. There… 
2000
2000
Effect of type‐selective inhibitors on cyclic nucleotide phosphodiesterase activity and insulin secretion in the clonal insulin secreting cell line BRIN‐BD11
The cyclic nucleotide phosphodiesterases (PDEs) present in an insulin secreting cell line, BRIN–BD11, were characterized using… 
2000
2000
Conserved amino acids in metal-binding motifs of PDE3A are involved in substrate and inhibitor binding.
The activity of phosphodiesterase (PDE)3A requires divalent cations. Putative metal-binding sites are expected at 2 highly… 
2000
2000
Cardiac type cGMP-inhibited phosphodiesterase (PDE3A) gene structure: similarity and difference to adipocyte type PDE3B gene.
Phosphodiesterase type 3 isoforms, PDE3A and 3B, are expressed primarily in cardiovascular and adipose tissues, respectively. We… 
1998
1998
Partial characterization of the active site human platelet cAMP phosphodiesterase, PDE3A, by site-directed mutagenesis.
Phosphodiesterases (PDE) are important for the downregulation of the intracellular level of the second messenger cyclic adenosine… 
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