Cyclic Nucleotide Phosphodiesterases, Type 3

Known as: cGMP-Inhibited Phosphodiesterase, cGMP Inhibited Cyclic Nucleotide Phosphodiesterase, Cyclic Nucleotide Phosphodiesterase PDE3 Family 
A cyclic nucleotide phosphodiesterase subfamily that is inhibited by the binding of CYCLIC GMP to an allosteric domain found on the enzyme and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2016
01219892016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
OBJECTIVE Brain amyloidosis is a key feature of Alzheimer's disease (AD). It also incorporates cerebrovascular amyloid β (Aβ) in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2012
2012
We assessed whether phosphodiesterase-III inhibition with cilostazol (Cil) augments the infarct size (IS)-limiting effects of… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
2010
2010
Vascular dementia is caused by blockage of blood supply to the brain, which causes ischemia and subsequent lesions primarily in… (More)
Is this relevant?
2004
2004
Combined poisoning with calcium channel blockers (CCBs) and beta-blockers is usually associated with severe hypotension and heart… (More)
Is this relevant?
2001
2001
BACKGROUND Phosphodiesterase III inhibitors (PDEIII-Is) improve the hemodynamic status of heart failure via inotropic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2000
2000
OBJECTIVE To determine whether vasopressin could be effective in treating the hypotension associated with phosphodiesterase III… (More)
Is this relevant?
1998
1998
Milrinone and 6-bromo-8(methylamino)imidazo[1,2a]pyrazine-2-carbonitrile [SCA40; phosphodiesterase (PDE) III inhibitors… (More)
Is this relevant?
1997
1997
BACKGROUND Phosphodiesterase III (PDE3) inhibitors are inotropic agents used to treat congestive heart failure (CHF) and are less… (More)
Is this relevant?
1993
1993
Phosphodiesterase III (cyclic GMP-inhibited, particulate, low Km) is believed to play a dominant role in the cyclic AMP breakdown… (More)
Is this relevant?
1991
1991
High levels of endogenous plasma catecholamines in patients with severe congestive heart failure induce a down-regulation of the… (More)
Is this relevant?