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PAX5 gene

Known as: PAX5, PAIRED BOX GENE 5, BSAP 
This gene is involved in the transcriptional regulation of target genes. It plays a role in B-cell differentiation, neural development and… 
National Institutes of Health

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Related topics

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B-Cell ActivationHomo sapiensNeurogenesisPaired Box Protein Pax-5, human

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PAX5 wt Allele

Papers overview

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2013
2013
Lineage-inappropriate PAX5 expression in t(8;21) acute myeloid leukemia requires signaling-mediated abrogation of polycomb repression.
The activation of B-cell-specific genes, such as CD19 and PAX5, is a hallmark of t(8;21) acute myeloid leukemia (AML) which… 
2012
2012
Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients
2010
2010
Aberrant expression of CD19 in AML with t(8;21) involves a poised chromatin structure and PAX5
Correct hematopoietic differentiation requires the tightly regulated execution of lineage-specific and stage-restricted gene… 
2009
2009
The promoter of the Immunoglobulin J Chain gene receives its authentic enhancer activity through the abutting MEF2 and PU.1 sites in a DNA-looping interaction.
2008
2008
2,3,7,8-Tetrachlorodibenzo-p-dioxin-Mediated Impairment of B Cell Differentiation Involves Dysregulation of Paired Box 5 (Pax5) Isoform, Pax5a
The persistent environmental contaminant and immunotoxicant, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), markedly suppresses… 
2008
2008
Development of cellular immune responses against PAX5, a novel target for cancer immunotherapy.
PAX5 is a member of the PAX family of developmental transcription factors with an important role in B-cell development. Its… 
2004
2004
Pax5 Activates Immunoglobulin Heavy Chain V to DJ Rearrangement in Transgenic Thymocytes
Mice deficient for the B cell–restricted transcription factor Pax5 show a defect in the VH to DJH rearrangement step of… 
2004
2004
Patterns of gene divergence and VL promoter activity in immunoglobulin light chain clusters of the channel catfish
The structure and genomic organization of V, J, and C segments in multiple gene clusters of the G class of catfish light (L… 
2002
2002
DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines.
1970
1970
Immunochemical studies on a laminaribiosyl-azoprotein conjugate.
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