PAX5 gene

Known as: PAX5, PAIRED BOX GENE 5, BSAP 
This gene is involved in the transcriptional regulation of target genes. It plays a role in B-cell differentiation, neural development and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Pax5 controls the identity and development of B cells by repressing lineage-inappropriate genes and activating B-cell-specific… (More)
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2011
2011
Pax5 is a critical regulator of B-cell commitment. Here, we identified direct Pax5 target genes by streptavidin-mediated ChIP… (More)
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Highly Cited
2011
Highly Cited
2011
As STAT5 is critical for the differentiation, proliferation, and survival of progenitor B cells, this transcription factor may… (More)
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2010
2010
Correct hematopoietic differentiation requires the tightly regulated execution of lineage-specific and stage-restricted gene… (More)
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Review
2008
Review
2008
The activity of the transcription factor paired box gene 5 (Pax5) is essential for many aspects of B lymphopoiesis including the… (More)
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Highly Cited
2007
Highly Cited
2007
Lineage commitment and differentiation to a mature cell type are considered to be unidirectional and irreversible processes under… (More)
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2003
2003
Progenitor B cells deficient in Pax5 are developmentally multipotent, suggesting that Pax5 is necessary to maintain commitment to… (More)
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Highly Cited
1997
Highly Cited
1997
The Pax5 gene coding for the transcription factor BSAP has an essential role in B lymphopoiesis and midbrain development. Here we… (More)
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Highly Cited
1996
Highly Cited
1996
Cytokine regulation of B cell development was analyzed using interleukin-2 (IL-2)-induced transcription of the J chain gene as a… (More)
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Highly Cited
1995
Highly Cited
1995
Medulloblatoma is a pediatric brain tumor originating in the human cerebellum. A collection of 23 medulloblastomas was analyzed… (More)
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