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Paired Box Protein Pax-5, human

Known as: B-Cell Specific Transcription Factor, PAX5, BSAP 
Paired box protein Pax-5 (391 aa, ~42 kDa) is encoded by the human PAX5 gene. This protein plays a role in B-cell differentiation, neural development… 
National Institutes of Health

Related topics

Related topics

13 relations
B-Cell ActivationDNA-Binding ProteinsGenes, RegulatorHomo sapiens

Broader (1)

paired box 5 protein (B-cell lineage specific activator)

Papers overview

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2017
2017
Aryl Hydrocarbon Receptor Activation Suppresses EBF1 and PAX5 and Impairs Human B Lymphopoiesis
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates biological responses to endogenous and… 
Highly Cited
2006
Highly Cited
2006
Zebrafish pax5 regulates development of the utricular macula and vestibular function
The zebrafish otic vesicle initially forms with only two sensory epithelia, the utricular and saccular maculae, which primarily… 
Highly Cited
2002
Highly Cited
2002
Altered mRNA expression of Pax5 and Blimp-1 in B cells in multiple myeloma.
Multiple myeloma (MM) is a plasma cell disorder that potentially initiates during an early stage of B-cell development. We… 
2002
2002
A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes
During mouse B‐cell development, Pax5 is an essential transcription factor that acts as an activator of B‐cell‐specific genes and… 
Highly Cited
2001
Highly Cited
2001
The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case.
The PAX5 gene, encoding the B-cell-specific activator protein, is a critical determinant of commitment to the B-lymphocyte… 
2000
2000
BSAP (Pax5)-importin alpha 1 (Rch1) interaction identifies a nuclear localization sequence.
BSAP (Pax5) is an essential transcription factor for early B cell and central nervous system development. In later B cell… 
Highly Cited
1999
Highly Cited
1999
AML1 (CBFα2) Cooperates with B Cell-specific Activating Protein (BSAP/PAX5) in Activation of the B Cell-specific BLK Gene Promoter*
AML1 plays a critical role during hematopoiesis and chromosomal translocations involving AML1 are commonly associated with… 
Highly Cited
1998
Highly Cited
1998
Deregulated PAX-5 transcription from a translocated IgH promoter in marginal zone lymphoma.
The PAX-5 gene codes for the transcription factor BSAP, which is expressed throughout B-cell development. Although loss-of… 
Highly Cited
1994
Highly Cited
1994
Specific recognition of the blk promoter by the B-lymphoid transcription factor B-cell-specific activator protein.
Several genes of the src family encode protein-tyrosine kinases that associate with the B-cell antigen receptor complex and are… 
Highly Cited
1992
Highly Cited
1992
Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.
BSAP has been identified previously as a transcription factor that is expressed at early, but not late, stages of B-cell… 
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