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PAWR gene

Known as: PROSTATE APOPTOSIS RESPONSE PROTEIN 4, TRANSCRIPTIONAL REPRESSOR PAR4, PRKC, Apoptosis, WT1, Regulator Gene 
This gene plays a role in repression of transcription. It is also involved in regulation of apoptosis.
National Institutes of Health

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Related topics

6 relations
PAWR proteinPAWR protein, humanPositive Regulation of ApoptosisTranscriptional Regulation

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PAWR wt Allele

Papers overview

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2014
2014
Regulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cells
The proapoptotic protein, prostate apoptosis response-4 (Par-4), acts as a tumor suppressor in prostate cancer cells. The serine… 
2011
2011
Stress-induced depressive behaviors are correlated with Par-4 and DRD2 expression in rat striatum
2011
2011
The Expression of Protease-Activated Receptor 2 and 4 in the Colon of Irritable Bowel Syndrome Patients
BackgroundIrritable bowel syndrome (IBS) pathophysiology has not been fully understood. Abnormalities of serine proteases have… 
2010
2010
Newborn platelets: Lower levels of protease-activated receptors cause hypoaggregability to thrombin
Newborn platelets show in vitro hypoaggregability to thrombin. Sensitivity of platelets to such a potent agonist is crucial for a… 
Highly Cited
2008
Highly Cited
2008
Bone Morphogenetic Protein-9 Induces Apoptosis in Prostate Cancer Cells, the Role of Prostate Apoptosis Response-4
Bone morphogenetic proteins (BMP) have been implicated in the development of bone metastases in prostate cancer. In this study… 
2005
2005
Immunohistochemical expression of Bcl2 is an independent predictor of time-to-biochemical failure in patients with clinically localized prostate cancer following radical prostatectomy.
BACKGROUND Whether the immunohistochemical expression (IHCE) of the bcl2, the p53 and of the prostate apoptosis response-4 (PAR4… 
Review
2002
Review
2002
Protease-activated receptors: the role of cell-surface proteolysis in signalling.
Certain extracellular proteases, derived from the circulation and inflammatory cells, can specifically cleave and trigger… 
2002
2002
Protease-activated receptor 4-like peptides bind to thrombin through an optimized interaction with the enzyme active site surface.
Highly Cited
2001
Highly Cited
2001
Regulation of Apoptosis during Neuronal Differentiation by Ceramide and b-Series Complex Gangliosides*
Lipid analysis of gestational day E14.5 mouse brain revealed elevation of ceramide to a tissue concentration that induced… 
2001
2001
Mechanism of trypsin‐induced contraction in the rat myometrium: the possible involvement of a novel member of protease‐activated receptor
The mechanism of trypsin‐induced contraction in the rat myometrium was investigated using front‐surface fluorimetry on fura‐PE3… 
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