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PAWR protein, human

Known as: Prostate Apoptosis Response Protein 4, Prostate Apoptosis Response 4 Protein, Transcriptional Repressor PAR4 
PRKC apoptosis WT1 regulator protein (340 aa, ~37 kDa) is encoded by the human PAWR gene. This protein plays a role in both the positive regulation… 
National Institutes of Health

Related topics

Related topics

13 relations
ApoptosisCeramide Signaling Pathway PIDGenes, RegulatorHomo sapiens

Broader (1)

PAWR protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Insulin-like growth factor-1 and 17β-estradiol down-regulate prostate apoptosis response-4 expression in MCF-7 breast cancer cells.
The PKC apoptosis WT1 regulator gene, also named prostate apoptosis response-4 (PAR-4), encodes a pro-apoptotic protein that… 
2008
2008
No association between prostate apoptosis response 4 gene (PAWR) in schizophrenia and mood disorders in a japanese population
Altered dopamine D2 receptor (D2R) is hypothesized to be a susceptibility factor for major psychosis. Recent studies showed that… 
2008
2008
Multimolecular complex of Par-4 and E2F1 binding to Smac promoter contributes to glutamate-induced apoptosis in human- bone mesenchymal stem cells
Neural cells undergo glutamate-induced apoptosis in ischaemic brain tissue, in which prostate apoptosis response-4 gene (Par-4… 
2007
2007
Protein expression and intracellular localization of prostate apoptosis response-4 (Par-4) are associated with apoptosis induction in nasopharyngeal carcinoma cell lines.
2007
2007
Regulation of the expression of prostate apoptosis response protein 4 (Par-4) in rat granulosa cells
The par-4 gene, directs the expression of a protein in the rat ventral prostate after apoptotic stimuli but not growth… 
2005
2005
Binding of Par-4 to the actin cytoskeleton is essential for Par-4/Dlk-mediated apoptosis.
2002
2002
p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition.
It has been reported that prostate apoptosis response-4 (PAR-4) binds to and inhibits protein kinase Czeta (PKCzeta) which… 
2001
2001
Evidence for the Involvement of Par-4 in Ischemic Neuron Cell Death
After a stroke many neurons in the ischemic brain tissue die by a process called apoptosis, a form of cell death that may be… 
2001
2001
Atypical protein kinase Czeta suppresses migration of mouse melanoma cells.
Mouse melanoma B16 F1 cells cultured in RPMI 1640 supplemented with the melanin precursors tyrosine and phenylalanine display… 
2000
2000
Par-4 induces cholinergic hypoactivity by suppressing ChAT protein synthesis and inhibiting NGF-inducibility of ChAT activity
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