Structures, biosynthesis, and functions of gangliosides--an overview.
- R. Yu, Yi-Tzang Tsai, T. Ariga, M. Yanagisawa
- Biology, ChemistryJournal of Oleo Science
- 2011
The structures, metabolism and functions of gangliosides are discussed, including those of cell surface microdomains with sphingomyelin and cholesterol from which they participate in cell-cell recognition, adhesion, and signal transduction.
Functional Roles of Gangliosides in Neurodevelopment: An Overview of Recent Advances
- R. Yu, Yi-Tzang Tsai, T. Ariga
- Biology, ChemistryNeurochemical Research
- 13 March 2012
This review focuses on recent advances on metabolic and functional studies of gangliosides in normal brain development and in certain neurological disorders.
Ganglioside Molecular Mimicry and Its Pathological Roles in Guillain-Barré Syndrome and Related Diseases
Guillain-Barre syndrome (GBS) is the most frequent cause of acute flaccid paralysis in humans, occurring with an annual incidence of 1 to 2 cases per 100,000 people. In recent years, studies have…
Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease--a review.
- T. Ariga, M. P. McDonald, R. Yu
- BiologyJournal of Lipid Research
- 1 June 2008
The possible involvement of gangliosides in the development of AD and the therapeutic potentials of Ganglioside metabolism are described, as well as the involvement of these microdomains in certain neurodegenerative diseases, such as AD.
GD3 ganglioside is a glycolipid characteristic of immature neuroectodermal cells
- J. Goldman, M. Hirano, R. Yu, T. Seyfried
- Biology, ChemistryJournal of Neuroimmunology
- 31 December 1985
Conserved domains of glycosyltransferases.
- D. Kapitonov, R. Yu
- Biology, ChemistryGlycobiology
- 1 October 1999
The present article presents the alignment of conserved NRD domains and also presents a brief overview of the analyzed glycosyltransferases, which comprise about 65% of all known sugar-nucleotide dependent (Leloir-type) and putative glycosYLtransferases in different databases.
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