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PARP2 gene

Known as: ADP-RIBOSYLTRANSFERASE 2, Poly (ADP-Ribose) Polymerase 2 Gene, ADP-RIBOSYLTRANSFERASE-LIKE 2 
This gene is involved in base excision repair of DNA.
National Institutes of Health

Related topics

Related topics

6 relations
Base Excision RepairDNA RepairPARP1 genePARP2 protein, human

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PARP2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
MP81-05 CRISPR SCREENING REVEALS GENES DRIVING RESISTANCE AND SENSITIVITY TO PARP INHIBITOR IN PROSTATE CANCER CELLS
INTRODUCTION AND OBJECTIVES: While next-generation anti-androgens have been developed, castration-resistant prostate cancer (CRPC… 
2018
2018
Determination of in vitro absorption in Caco-2 monolayers of anticancer Ru(II)-based complexes acting as dual human topoisomerase and PARP inhibitors
Due to their unique and versatile biochemical properties, ruthenium-based compounds have emerged as promising anticancer agents… 
2016
2016
An imputation-based genome-wide association study on traits related to male reproduction in a White Duroc × Erhualian F2 population.
Boar reproductive traits are economically important for the pig industry. Here we conducted a genome-wide association study (GWAS… 
2016
2016
Design and Molecular modeling of some phthalazinone derivatives as PARP2 Inhibitors
Review
2014
Review
2014
Role of PARP2 in DNA repair
The genome stability of higher eukaryotes depends largely on the functioning of the DNA repair systems. In turn, the precise… 
2013
2013
Nonhomologous end-joining promotes resistance to DNA damage in the absence of an ADP-ribosyltransferase that signals DNA single strand breaks
Summary ADP-ribosylation of proteins at DNA lesions by ADP-ribosyltransferases (ARTs) is an early response to DNA damage. The… 
2012
2012
Functional regulation of proteins involved in genomic maintenance by poly(ADP-ribose)
Poly(ADP-ribosyl)ation (PARylation) is a post translational modification which is catalysed by poly(ADP-ribose) polymerases… 
2011
2011
The PARP inhibitor PJ34 causes a PARP1-independent, p21 dependent mitotic arrest.
2006
2006
Chromosomal imbalances and their target genes in gastrointestinal stromal tumors
Gastrointestinal stromal tumor (GIST) is a mesenchymal sarcoma of the gastrointestinal tract. The tumors characteristically… 
2001
2001
PARP 2 Identified Using a Cell-based Screen in Yeast Novel Inhibitors of Poly ( ADP-ribose ) Polymerase / PARP 1 and Updated
Multicellular organisms must have means of preserving their genomic integrity or face catastrophic consequences such as… 
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