PARP2 gene

Known as: ADP-RIBOSYLTRANSFERASE 2, Poly (ADP-Ribose) Polymerase 2 Gene, ADP-RIBOSYLTRANSFERASE-LIKE 2 
This gene is involved in base excision repair of DNA.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
01219992017

Papers overview

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2017
2017
Double strand breaks (DSBs) are one of the most toxic lesions to cells. DSB repair by the canonical non-homologous end-joining (C… (More)
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Highly Cited
2014
Highly Cited
2014
Anti-PARP drugs were initially developed as catalytic inhibitors to block the repair of DNA single-strand breaks. We recently… (More)
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2011
2011
PARP-2 is a member of the poly(ADP-ribose) polymerase family, with some activities similar to those of PARP-1 but with other… (More)
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Review
2011
Review
2011
  • Joyce O ’ Shaughnessy
  • Oncology
  • 2011
Joyce O’Shaughnessy, MD, of the Baylor Sammons Cancer Center in Dallas, discussed this ongoing research at the American Society… (More)
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2009
2009
e22114 Background: Breast cancer susceptibility gene (BRCA1) is a tumor suppressor gene whose mutation is associated with the… (More)
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2006
2006
RNA interference (RNAi) is an extremely powerful and widely used gene silencing approach for reverse functional genomics and… (More)
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2004
2004
Diffuse brain invasion is a major reason for poor prognosis of glioma patients. The molecular mechanisms underlying infiltration… (More)
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2001
2001
Poly(ADP-ribose) polymerase 2 (PARP-2) is a DNA damage-dependent enzyme that belongs to a growing family of enzymes seemingly… (More)
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Highly Cited
1999
Highly Cited
1999
Poly(ADP-ribosylation) is a post-translational modification of nuclear proteins in response to DNA damage that activates the base… (More)
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1999
1999
Posttranscriptional modification of nuclear proteins by poly(ADP-ribosyl)ation in response to DNA strand breaks plays an… (More)
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