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PARP1 gene
Known as:
PARP1
, ADPRT1
, ADP-RIBOSYLTRANSFERASE
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This gene is involved in cellular repair and apoptosis.
National Institutes of Health
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Related topics
Related topics
16 relations
ADP Ribose Transferases
Base Excision Repair
DNA Repair
PARP1 protein, human
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PARP1 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Preliminary Study on the Significance of BRCA1 and PARP1 Immunohistochemical Expression in Ovarian Cancer
L. Resta
,
M. A. Cascarano
,
+4 authors
A. Marzullo
2018
Corpus ID: 55106781
Role of BRCA1 and PARP1 has been studied by immunohistochemistry in a cohort of ovarian cancers. Their expression has been…
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2015
2015
An LRP 16-containing preassembly complex contributes to NF-B activation induced by DNA double-strand breaks
Zhiqiang Wu
,
Chunmeng Wang
,
+7 authors
W. Han
2015
Corpus ID: 67757060
The activation of NFB has emerged as an important mechanism for the modulation of the response to DNA double-strand breaks (DSBs…
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2015
2015
Ингибиторы parp1: разработка противоопухолевых препаратов
Н. В. Малюченко
,
Ю Р Котова
,
+4 authors
Ленинские Горы
2015
Corpus ID: 87926918
РЕФЕРАТ Одной из перспективных молекулярных мишеней для поиска противоопухолевых средств является поли(АDP-рибозо)полимераза 1…
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2015
2015
Abstract CT326: Pharmacokinetic/pharmacodynamic study of sequence specificity of the PARP inhibitor, olaparib and carboplatin in recurrent women's cancers
Victoria L. Chiou
,
C. Annunziata
,
+7 authors
Jung-Min Lee
2015
Corpus ID: 78755810
Background: Olaparib/carboplatin are active in gBRCA1/2m+ or BRCA-like breast and ovarian cancer (Br/OvCa). Our in vitro data…
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Review
2015
Review
2015
New Biologic Frontiers in Ovarian Cancer: Olaparib and PARP Inhibition
H. Dalton
,
R. Coleman
2015
Corpus ID: 69112374
Introduction Poly (ADP-ribose) polymerase (PARP) inhibition was first introduced as a novel cancer-targeting strategy in 2005…
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2012
2012
Therapeutics , Targets , and Chemical Biology An NQO 1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP 1-Induced Programmed Necrosis
Xiumei Huang
,
Ying Dong
,
+10 authors
D. Boothman
2012
Corpus ID: 1820070
Agents, such as b-lapachone, that target the redox enzyme, NAD(P)H:quinone oxidoreductase 1 (NQO1), to induce programmed necrosis…
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Review
2008
Review
2008
Irinotecan Pharmacogenetics : Influence of PharmacodynamicGenes
J. Hoskins
,
EugenioMarcuello
,
+7 authors
andMontserrat Baiget
2008
Corpus ID: 16902932
Purpose: Irinotecan is an important drug for the treatment of solid tumors. Although genes involved in irinotecan…
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2007
2007
Role of caspases in cleavage of lamin A/C and PARP during apoptosis in macrophages infected with a periodontopathic bacterium
沖永 敏則
2007
Corpus ID: 68747468
2007
2007
Polymorphic markers Val762Ala and Leu54Phe of the ADPRT1 gene associated with chronic glomerulonephritis in Russian patients from Moscow
A. Shestakov
,
E. Kamyshova
,
E. Petrosyan
,
I. Kutyrina
,
K. V. Savostyanov
,
V. Nosikov
Russian Journal of Genetics
2007
Corpus ID: 25530608
A comparative analysis of allele and genotype distribution of polymorphic markers Val762Ala and Leu54Phe of ADPRT1 gene encoding…
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2000
2000
The Tyrosine Kinase Inhibitor CGP 57148 ( ST 1 571 ) Induces Apoptosis in BCR-ABL-positive Cells by Down-Regulating BCL-X 1
Carsten Oetzel
,
T. Jonuleit
,
+5 authors
W. Aulitzky
2000
Corpus ID: 18568258
CGP 57148 is a potent inhibitor of the ABL protein tyrosine kinase and a promising new compound for the treatment of a variety of…
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