PARP1 wt Allele

Known as: ADPRT 1, ADPRT1, pADPRT-1 
Human PARP1 wild-type allele is located within 1q41-q42 and is approximately 47 kb in length. This allele, which encodes poly [ADP-ribose] polymerase… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
UNLABELLED There is a need to improve treatments for metastatic breast cancer. Here, we show the activation of the… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE To determine the safety and tolerability of olaparib with cisplatin and gemcitabine, establish the maximum tolerated dose… (More)
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Highly Cited
2005
Highly Cited
2005
It is well established that tissue damage and functional outcome after experimental or clinical stroke are shaped by biologic sex… (More)
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Highly Cited
2003
Highly Cited
2003
Nuclear factor kappaB (NF-kappaB) plays an important role in the transcriptional regulation of genes involved in inflammation and… (More)
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Highly Cited
2003
Highly Cited
2003
Severe hypoglycemia causes neuronal death and cognitive impairment. Evidence suggests that hypoglycemic neuronal death involves… (More)
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Highly Cited
2002
Highly Cited
2002
The DNA damage dependence of poly(ADP-ribose) polymerase-2 (PARP-2) activity is suggestive of its implication in genome… (More)
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Highly Cited
2002
Highly Cited
2002
Grape seed extract (GSE), rich in the bioflavonoids commonly known as procyanidins, is one of the most commonly consumed dietary… (More)
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Highly Cited
1999
Highly Cited
1999
A protocol is prescribed for clinical reference dosimetry of external beam radiation therapy using photon beams with nominal… (More)
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Highly Cited
1997
Highly Cited
1997
Mice lacking the gene encoding poly(ADP-ribosyl) transferase (PARP or ADPRT) display no phenotypic abnormalities, although aged… (More)
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Highly Cited
1992
Highly Cited
1992
Poly(ADP-ribosyl)ation is a eukaryotic posttranslational modification of proteins that is strongly induced by the presence of DNA… (More)
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