Skip to search formSkip to main contentSkip to account menu

PARP2 protein, human

Known as: PARP-2 protein, human, PARP2, NAD(+) ADP-Ribosyltransferase 2 
Poly [ADP-ribose] polymerase 2 (583 aa, ~66 kDa) is encoded by the human PARP2 gene. This protein is involved in the initiation of DNA repair.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
TPS1107 Background: Poly-ADP-ribose polymerase (PARP) represents a family of enzymes of which at least two (PARP1 and PARP2) play… 
Highly Cited
2012
Highly Cited
2012
ABSTRACT On the cellular level, oxidative stress may cause various responses, including autophagy and cell death. All of these… 
2011
2011
3041 Background: Veliparib is a potent, oral inhibitor of PARP-1 and PARP-2. We previously reported phase I results of veliparib… 
2010
2010
We recently demonstrated that poly(ADP-ribose) polymerase (PARP)-1 is involved in angiogenesis and tumour aggressiveness. In this… 
2010
2010
3000 Background: ABT-888 is a potent, oral inhibitor of PARP-1 and PARP-2. In preclinical studies, ABT-888 enhances the… 
Review
2006
Review
2006
Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent posttranslational modification of histones and other nuclear proteins… 
Highly Cited
2004
Highly Cited
2004
Regulating the topological state of DNA is a vital function of the enzyme DNA topoisomerase I. However, when acting on damaged…