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P2RY2 wt Allele

Known as: Purinergic Receptor P2Y, G-Protein Coupled, 2 wt Allele, HP2U, P2RU1 
Human P2RY2 wild-type allele is located within 11q13.5-q14.1 and is approximately 18 kb in length. This allele, which encodes P2Y purinoceptor 2, is… 
National Institutes of Health

Related topics

Related topics

4 relations
G Protein-Coupled Receptor SignalingLigand BindingReceptor SignalingSignal Transduction

Papers overview

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2017
2017
Regulación de sistema ubiquitina-proteasoma por los receptores purinérgicos en el sistema nervioso central
Los nucleotidos, que se comportan como neurotransmisores en el SNC, se encuentran implicados en una gran variedad de procesos… 
2016
2016
A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism.
2016
2016
P2Y2 nucleotide receptor mediates arteriogenesis in a murine model of hind limb ischemia.
2016
2016
P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells
Polycystic kidney diseases are characterized by numerous renal cysts that continuously enlarge resulting in compression of intact… 
2014
2014
“ The Role of the P 2 Y 2 Nucleotide Receptor in Salivary Gland Regeneration ” presented
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Highly Cited
2012
Highly Cited
2012
Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation, migration, and engraftment in immunodeficient mice.
Extracellular ATP and UTP nucleotides increase the proliferation and engraftment potential of normal human hematopoietic stem… 
2007
2007
The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12.
The P2Y2 nucleotide receptor (P2Y2R) interacts with alpha v integrins to activate G(o) and induce chemotaxis in human 1321N1… 
1998
1998
ATP and UTP activate calcium-mobilizing P2U-like receptors and act synergistically with interleukin-1 to stimulate prostaglandin E2 release from human rheumatoid synovial cells.
OBJECTIVE To pharmacologically and functionally characterize calcium-mobilizing purine receptors on adherent human rheumatoid… 
1998
1998
Anion photoelectron spectroscopy of I 2 2 and I 2 2 – Arn „ n 5 1 – 14 , 16 , 20 ... clusters
We report the mass-selected anion photoelectron spectra of I 2 2 and the weakly bound clusters I 2 2 •Arn (n51 – 14, 16, 20… 
1996
1996
Activation of apical P2U purine receptors permits inhibition of adrenaline-evoked cyclic AMP accumulation in cultured equine sweat gland epithelial cells.
Experiments were undertaken using cultured equine sweat gland epithelial cells that express purine receptors belonging to the P2U… 
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