FAQ

Osteogenesis Imperfecta

Known as: Fragilitas Ossium, Brittle bone disease, Ossiums, Fragilitas 
COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and… (More)

Topic mentions per year

Topic mentions per year

1935-2018
010020030019352017

Related topics

Related topics

39 relations

Narrower (5)

Al Gazali Sabrinathan Nair syndromeLobstein's DiseaseLowry Maclean syndromeOsteogenesis imperfecta, Levin type
(More)
Bone DiseasesCOL1A1 geneCOL1A1 wt AlleleCOL1A2 gene
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Broader (5)

Bone Diseases, DevelopmentalCollagen DiseasesCongenital osteodystrophyOsteoporosis
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Osteogenesis Imperfecta
Skeletal bone
Osteoporosis
radiotherapeutic
Hereditary Diseases
Calcitonin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Extreme Learning Machine for Regression and Multiclass Classification
Due to the simplicity of their implementations, least square support vector machine (LS-SVM) and proximal support vector machine… (More)
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Highly Cited
2007
Highly Cited
2007
Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta
A recessive form of severe osteogenesis imperfecta that is not caused by mutations in type I collagen has long been suspected… (More)
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Highly Cited
2006
Highly Cited
2006
CRTAP Is Required for Prolyl 3- Hydroxylation and Mutations Cause Recessive Osteogenesis Imperfecta
Prolyl hydroxylation is a critical posttranslational modification that affects structure, function, and turnover of target… (More)
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Highly Cited
2005
Highly Cited
2005
Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta.
BACKGROUND Mesenchymal stem cells (MSC) are progenitors of mesenchymal tissues such as bone, cartilage, and adipose. Adult human… (More)
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Highly Cited
2002
Highly Cited
2002
Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone.
Treatment with isolated allogeneic mesenchymal cells has the potential to enhance the therapeutic effects of conventional bone… (More)
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Highly Cited
2001
Highly Cited
2001
Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta.
Preclinical models have shown that transplantation of marrow mesenchymal cells has the potential to correct inherited disorders… (More)
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Highly Cited
2000
Highly Cited
2000
Type V osteogenesis imperfecta: a new form of brittle bone disease.
Osteogenesis imperfecta (OI) is commonly subdivided into four clinical types. Among these, OI type IV clearly represents a… (More)
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Highly Cited
1999
Highly Cited
1999
Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
In principle, transplantation of mesenchymal progenitor cells would attenuate or possibly correct genetic disorders of bone… (More)
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Highly Cited
1998
Highly Cited
1998
Cyclic administration of pamidronate in children with severe osteogenesis imperfecta.
BACKGROUND Severe osteogenesis imperfecta is a disorder characterized by osteopenia, frequent fractures, progressive deformity… (More)
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Highly Cited
1979
Highly Cited
1979
Genetic heterogeneity in osteogenesis imperfecta.
An epidemiological and genetical study of osteogenesis imperfecta (OI) in Victoria, Australia confirmed that there are at least… (More)
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