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A new paradigm has emerged for osteogenesis imperfecta as a collagen-related disorder. The more prevalent autosomal dominant… Expand Osteogenesis imperfecta (OI) is a generalized disorder of connective tissue characterized by fragile bones and easy… Expand Prolyl hydroxylation is a critical posttranslational modification that affects structure, function, and turnover of target… Expand Treatment with isolated allogeneic mesenchymal cells has the potential to enhance the therapeutic effects of conventional bone… Expand Preclinical models have shown that transplantation of marrow mesenchymal cells has the potential to correct inherited disorders… Expand ZnO typifies a class of materials that can be doped via native defects in only one way: either n type or p type. We explain this… Expand BACKGROUND
Severe osteogenesis imperfecta is a disorder characterized by osteopenia, frequent fractures, progressive deformity… Expand Marrow stromal cells from wild-type mice were infused into transgenic mice that had a phenotype of fragile bones resembling… Expand The observed fit of bone mass to a healthy animal's typical mechanical usage indicates some mechanism or mechanisms monitor that… Expand An epidemiological and genetical study of osteogenesis imperfecta (OI) in Victoria, Australia confirmed that there are at least… Expand