Bone mineralization in an osteogenesis imperfecta mouse model studied by small-angle x-ray scattering.

Abstract

We have studied the size and orientation of mineral crystals in cortical bone of oim/oim mice, which are known to produce only alpha 1(I) collagen homotrimers and which may serve as a model for human osteogenesis imperfecta. Long bones (femur and tibia) from young (5 wk old) oim/oim mice and from unaffected heterozygous counterparts were investigated by… (More)

Topics

8 Figures and Tables

Cite this paper

@article{Fratzl1996BoneMI, title={Bone mineralization in an osteogenesis imperfecta mouse model studied by small-angle x-ray scattering.}, author={Peter Fratzl and Oskar Paris and Klaus Klaushofer and William J. Landis}, journal={The Journal of clinical investigation}, year={1996}, volume={97 2}, pages={396-402} }