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Ornithine Decarboxylase

Known as: Ornithine Decarboxylase [Chemical/Ingredient], Ornithine Decarboxylase 1, L-Ornithine carboxy-lyase 
A pyridoxal-phosphate protein, believed to be the rate-limiting compound in the biosynthesis of polyamines. It catalyzes the decarboxylation of… 
National Institutes of Health

Related topics

Related topics

15 relations
Biogenic Amine Metabolic ProcessEflornithineEnzyme GeneIn Blood

Broader (1)

Carboxy-Lyases

Papers overview

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Highly Cited
1987
Highly Cited
1987
Transcriptional activation of mammalian ornithine decarboxylase during stimulated growth
Cloned ornithine decarboxylase (ODC) (EC 4.1.1.17) cDNA was used to investigate the mechanisms which mediate the mitogenic… 
Highly Cited
1985
Highly Cited
1985
Nucleotide sequence of murine ornithine decarboxylase mRNA.
Ornithine decarboxylase (OrnDCase; L-ornithine carboxy-lyase, EC 4.1.1.17) is the first and rate-limiting enzyme in the… 
Highly Cited
1982
Highly Cited
1982
Purification of ornithine decarboxylase from kidneys of androgen-treated mice.
Ornithine decarboxylase has been purified to homogeneity from kidneys of androgen-treated mice. Such kidneys have an enzyme… 
Review
1982
Review
1982
Polyamines in mammalian tumors. Part II.
Review
1980
Review
1980
Ornithine decarboxylase as a biological and pharmacological tool.
Ornithine decarboxylase, the initial enzyme in the polyamine biosynthetic pathway, is induced in target tissues in response to a… 
Highly Cited
1980
Highly Cited
1980
Role of ornithine decarboxylase in cardiac growth and hypertrophy.
Inhibition of cardiac ornithine decarboxylase (ODC) by alpha-difluoromethylornithine (DFMO) did not prevent normal cardiac growth… 
Highly Cited
1979
Highly Cited
1979
A possible naturally occurring tumor promoter, teleocidin B from Streptomyces.
Highly Cited
1979
Highly Cited
1979
Impeded cerebellar development and reduced serum thyroxine levels associated with fetal alcohol intoxication
Highly Cited
1978
Highly Cited
1978
Effect of alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on L1210 leukemia in mice.
Abstract α-Difluoromethylornithine monohydrochloride (α-DFMO), an enzyme-activated irreversible inhibitor of ornithine… 
Highly Cited
1970
Highly Cited
1970
Growth hormone induction of ornithine decarboxylase in rat liver.
The effect of growth hormone on hepatic ornithine decarboxylase (L-ornithine carboxy- lyase, EC 4.1.1.17) (ORD) activity was… 
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