FAQ

Ornithine Decarboxylase Inhibitors

Known as: Decarboxylase Inhibitors, Ornithine, Inhibitors, Ornithine Decarboxylase, Ornithine Decarboxylase Inhibitor 
Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1972-2016
051019722016

Related topics

Related topics

18 relations

Narrower (14)

1-aminooxy-3-aminopropane1-aminooxy-4-aminobutane2-(fluoromethyl)dehydroornithine methyl ester2-amino-5-iodoacetamidopentanoic acid
(More)
In Bloodchemical synthesisisolation & purification analysisstandards characteristics

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Ornithine Decarboxylase Inhibitors
In Blood
chemical synthesis
Eflornithine
standards characteristics
alpha-hydrazinoornithine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors.
A series of novel aromatic derivatives based on the structure of methylglyoxal bis(guanylhydrazone) (MGBG) was examined for… (More)
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1992
1992
Cure of murine Trypanosoma brucei rhodesiense infections with an S-adenosylmethionine decarboxylase inhibitor.
The compound 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine (MDL73811), a potent inhibitor of S-adenosylmethionine… (More)
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Highly Cited
1990
Highly Cited
1990
Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a nonsteroidal antiinflammatory drug with D,L-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor…
The effect of three levels of piroxicam and three levels of D,L-alpha-difluoromethylornithine (DFMO) fed individually and in… (More)
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1987
1987
Plasmodium falciparum and Plasmodium berghei: effects of ornithine decarboxylase inhibitors on erythrocytic schizogony.
Five ornithine decarboxylase inhibitors: alpha-difluoromethylornithine (DFMO) (eflornithine); alpha-monofluoromethyl-3,4… (More)
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1987
1987
Impairment of macrophage function by inhibitors of ornithine decarboxylase activity.
The effects of irreversible inhibition of ornithine decarboxylase on the capacity of murine macrophages to take up a protozoan… (More)
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1987
1987
Inhibition of polyamine oxidase improves the antitumoral effect of ornithine decarboxylase inhibitors.
Specific inhibition of ornithine decarboxylase activity prevents the formation of putrescine from ornithine and decreases… (More)
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1986
1986
Comparison of the effects of an ornithine decarboxylase inhibitor on the intestinal epithelium and on intestinal tumors.
Ornithine decarboxylase (ODC) catalyzes the rate-limiting step in the synthesis of polyamines, it has a short half-life, and its… (More)
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1984
1984
Involvement of histamine in growth of mouse and rat tumors: antitumoral properties of monofluoromethylhistidine, an enzyme-activated irreversible inhibitor of histidine decarboxylase.
The present study suggests that newly synthesized histamine is involved in the development of some animal tumors (e.g., Lewis… (More)
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1982
1982
Ornithine decarboxylase: essential in proliferation but not differentiation of human promyelocytic leukemia cells.
The ornithine decarboxylase inhibitor DL-alpha-difluoromethyl ornithine inhibited a proliferation-associated increase in… (More)
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1981
1981
Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor.
alpha-Difluoromethylornithine (DFMO), an enzyme-activated irreversible inhibitor of ornithine decarboxylase, was used alone and… (More)
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