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Ornithine Decarboxylase Inhibitors

Known as: Decarboxylase Inhibitors, Ornithine, Inhibitors, Ornithine Decarboxylase, Ornithine Decarboxylase Inhibitor 
Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction… 
National Institutes of Health

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1-aminooxy-3-aminopropane1-aminooxy-4-aminobutane2-(fluoromethyl)dehydroornithine methyl ester2-amino-5-iodoacetamidopentanoic acid
In Bloodaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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1995
1995
Ornithine decarboxylase inhibitor attenuates NaCl enhancement of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine.
The effects of combined administration of NaCl and the ornithine decarboxylase (ODC) inhibitor 1,3-diaminopropane (DAP) on the… 
1987
1987
Implication of Ornithine Decarboxylase and Polyamines in Pancreatic Growth of Neonatal Rats
The current study examines the effects of α-difluoromethylornithine (DFMO), an irreversible ornithine decarboxylase inhibitor, on… 
1986
1986
Restoration of the polyamine contents in rat hepatoma tissue-culture cells after inhibition of polyamine biosynthesis. Relationship with cell proliferation.
The restoration of the polyamine content in polyamine-deficient rat hepatoma tissue-culture (HTC) cells, after short duration of… 
1985
1985
Independent regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in methylthioadenosine phosphorylase-deficient malignant murine lymphoblasts.
The control of polyamine synthesis in neoplastic cells is complex and incompletely understood. Using murine lymphoma cells… 
1984
1984
Effects of polyamine depletion on proliferation and differentiation of murine erythroleukemia cells.
The polyamines putrescine, spermidine, and spermine have been implicated in the regulation of both cell proliferation and… 
1984
1984
Physiological effects in bovine lymphocytes of inhibiting polyamine synthesis with ethylglyoxal bis(guanylhydrazone).
Previous results have suggested that ethylglyoxal bis(guanylhydrazone) is a more specific inhibitor of polyamine biosynthesis… 
1984
1984
Successful treatment of lethal protozoal infections with the ornithine decarboxylase inhibitor, alpha-difluoromethylornithine.
1984
1984
Comparison of specificity of inhibition of polyamine synthesis in bovine lymphocytes by ethylglyoxal bis(guanylhydrazone) and methylglyoxal bis(guanylhydrazone).
Ethylglyoxal bis(guanylhydrazone) (EGBG) was compared as an inhibitor of polyamine biosynthesis with methylglyoxal bis… 
1983
1983
In vivo effects of alpha-DL-difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei.
The EATRO 110 isolate of Trypanosoma brucei brucei was grown in rats for 60 h and the animals treated with the ornithine… 
1980
1980
The effect of inhibitors of ornithine decarboxylase on DNA synthesis in mouse mammary gland in culture. The importance of osmolarity of the medium and of the initial intracellular level of putrescine…
In cultured mammary explants from both virgin and midpregnant mice which contained a low and a high initial level of putrescine…