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Ornithine Decarboxylase Inhibitors
Known as:
Decarboxylase Inhibitors, Ornithine
, Inhibitors, Ornithine Decarboxylase
, Ornithine Decarboxylase Inhibitor
Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction…
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National Institutes of Health
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Related topics
Related topics
18 relations
Narrower (14)
1-aminooxy-3-aminopropane
1-aminooxy-4-aminobutane
2-(fluoromethyl)dehydroornithine methyl ester
2-amino-5-iodoacetamidopentanoic acid
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chemical synthesis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Contemporary medical therapy for polycystic ovary syndrome
Michael Lanham
,
D. Lebovic
,
S. E. Domino
International journal of gynaecology and…
2006
Corpus ID: 22010208
2004
2004
Cellular mechanisms mediating the anti-invasive properties of the ornithine decarboxylase inhibitor α-difluoromethylornithine (DFMO) in human breast cancer cells
A. Manni
,
S. Washington
,
D. Mauger
,
D. A. Hackett
,
M. Verderame
Clinical and Experimental Metastasis
2004
Corpus ID: 22636154
We have shown that inhibition of polyamine biosynthesis with α-difluoromethylornithine (DFMO) reduces in vitro invasiveness and…
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1999
1999
The pathogenesis and modulation of the post-treatment reactive encephalopathy in a mouse model of Human African Trypanosomiasis
P. Kennedy
Journal of Neuroimmunology
1999
Corpus ID: 43486357
1996
1996
Polyamine content of Pneumocystis carinii and response to the ornithine decarboxylase inhibitor DL-alpha-difluoromethylornithine
Salim Merali
,
A. Clarkson
Antimicrobial Agents and Chemotherapy
1996
Corpus ID: 22038153
Difluoromethylornithine (DFMO; eflornithine hydrochloride [Ornidyl]), a suicide inhibitor of the key polyamine biosynthesis…
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1990
1990
Inhibition of the dimorphic transition of Candida albicans by the ornithine decarboxylase inhibitor 1,4-diaminobutanone: alterations in the glycoprotein composition of the cell wall.
J. Martinez
,
J. Lopez-Ribot
,
M. Gil
,
R. Sentandreu
,
J. Ruiz-Herrera
Journal of General Microbiology
1990
Corpus ID: 26828635
Hyphal development in Candida albicans was selectively blocked by the ornithine decarboxylase competitive inhibitor 1,4…
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Highly Cited
1989
Highly Cited
1989
Differential response to treatment with the bis(ethyl)polyamine analogues between human small cell lung carcinoma and undifferentiated large cell lung carcinoma in culture.
R. Casero
,
S. J. Ervin
,
Paul Celano
,
S. Baylin
,
Raymond J. Bergeron
Cancer Research
1989
Corpus ID: 2627678
1988
1988
Regulation of mammalian S-adenosylmethionine decarboxylase.
A. Pegg
,
T. Kameji
,
A. Shirahata
,
B. Stanley
,
R. Madhubala
,
A. Pajunen
Advances in Enzyme Regulation
1988
Corpus ID: 23707199
1987
1987
Inhibition of polyamine oxidase improves the antitumoral effect of ornithine decarboxylase inhibitors.
N. Claverie
,
J. Wagner
,
B. Knodgen
,
N. Seiler
Anticancer Research
1987
Corpus ID: 34507441
Specific inhibition of ornithine decarboxylase activity prevents the formation of putrescine from ornithine and decreases…
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1985
1985
Independent regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase in methylthioadenosine phosphorylase-deficient malignant murine lymphoblasts.
M. Kubota
,
E. Kajander
,
D. Carson
Cancer Research
1985
Corpus ID: 18955415
The control of polyamine synthesis in neoplastic cells is complex and incompletely understood. Using murine lymphoma cells…
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1985
1985
Disruption of the blood‐brain barrier in hyperammonemic coma and the pharmacologic effects of dexamethasone and difluoromethyl ornithine
E. S. Sears
,
D. McCandless
,
M. D. Chandler
Journal of Neuroscience Research
1985
Corpus ID: 21517442
Both hyperammonemia and blood‐brain barrier (BBB) breakdown have been implicated in the evolution of hepatic encephalopathy. To…
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