1-aminooxy-3-aminopropane

Known as: 1-Propanamine, 3-(aminooxy)-, 3-aminooxy-1-propanamine 
 
National Institutes of Health

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2003
2003
AbstractThe effects of the putrescine analogue 1-aminooxy-3-aminopropane on fungal polyamine metabolism were evaluated using… Expand
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2001
2001
Polyamine synthesis (by the action of ornithine decarboxylase [ODC] and S-adenosylmethionine decarboxylase [SAMDC]) and polyamine… Expand
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1997
1997
The activity of ornithine decarboxylase, the key enzyme in the synthesis of polyamines, is essential for proliferation and… Expand
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1994
1994
1- or 3-methylated derivatives and oximes of 1-aminooxy-3-aminopropane (APA) with pyridoxal (PL) and pyridoxal 5'-phosphate (PLP… Expand
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1993
1993
  • Helmut Mett, Jaroslav Stanek, +5 authors Urs Regenass
  • Cancer Chemotherapy and Pharmacology
  • 1993
Analogues of 3-aminooxy-1-propanamine proved to be highly potent and selective inhibitors of ornithine decarboxylase (ODC). The… Expand
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1991
1991
Hypoosmotic stress is a potent inducer of ornithine decarboxylase (ODC) activity in a variety of mammalian cells, but the… Expand
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1990
1990
The uptake, catabolism, and release of H-labeled 1-aminooxy-3-aminopropane, a new putrescine analog shown to be a potent… Expand
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1990
1990
The kinetics of inactivation of adenosylmethionine decarboxylase of rat liver and of baby hamster kidney cells (BHK21/C31) by 1… Expand
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1986
1986
1-Aminooxy-3-aminopropane (APA) was shown to be a potent competitive inhibitor (Ki = 1.0 nM) of partially purified Escherichia… Expand
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1985
1985
1-Aminooxy-3-aminopropane was shown to be a potent competitive inhibitor (Ki = 3.2 nM) of homogenous mouse kidney ornithine… Expand
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