Oncogene E1A

Known as: E1A 
Viral Oncogene E1A encodes E1A Protein, a regulator of early viral gene transcription. E1A interacts with diverse cellular proteins to override host… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
Adenovirus e1a induces quiescent human cells to replicate. We found that e1a causes global relocalization of the RB… (More)
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Highly Cited
2001
Highly Cited
2001
Here, we report the identification of a new E1A binding protein complex that is essential for E1A-mediated transformation. Its… (More)
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Highly Cited
1998
Highly Cited
1998
The adenovirus E1A oncogene activates p53 through a signaling pathway involving the retinoblastoma protein and the tumor… (More)
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Highly Cited
1996
Highly Cited
1996
The adenoviral oncoprotein E1A induces progression through the cell cycle by binding to the products of the p300/CBP and… (More)
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Highly Cited
1995
Highly Cited
1995
THE cellular protein p300 is a target of the adenoviral El A oncoprotein and is thought to participate in preventing the GO/G1… (More)
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Highly Cited
1993
Highly Cited
1993
Transformation of primary rodent cells by the adenovirus E1A and E1B oncogenes is a two-step process, where E1A-dependent… (More)
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Highly Cited
1993
Highly Cited
1993
Oncogenic transformation by human adenoviruses requires early regions 1A and 1B (E1A and E1B) and provides a model of multistep… (More)
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Highly Cited
1990
Highly Cited
1990
Adenovirus infection activates the E2F transcription factor, in part through the formation of a heteromeric protein complex… (More)
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Highly Cited
1990
Highly Cited
1990
The adenovirus E1a protein stimulates transcription of viral early genes. Recent experiments indicate that E1a contains a… (More)
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Highly Cited
1988
Highly Cited
1988
One of the cellular targets implicated in the process of transformation by the adenovirus E1A proteins is a 105K cellular protein… (More)
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