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Oncogene, RET

Known as: MEN2B, RET, ret oncogene 
Human Oncogene RET is a mutated variant of RET Gene, which encodes Tyrosine-Protein Kinase Receptor RET, a type I membrane protein receptor for Glial… 
National Institutes of Health

Related topics

Related topics

13 relations
10q11.2Familial medullary thyroid carcinomaHomo sapiensMedullary carcinoma of thyroid

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations
Purpose: While multikinase inhibitors with RET activity are active in RET-rearranged thyroid and lung cancers, objective response… 
Highly Cited
2001
Highly Cited
2001
Activation of BMK1 via tyrosine 1062 in RET by GDNF and MEN2A mutation.
Big mitogen-activated protein kinase 1 (BMK1) is a new member of mitogen-activated protein kinase (MAPK) family. In the present… 
2001
2001
The Sensitivity of Activated Cys Ret Mutants to Glial Cell Line-Derived Neurotrophic Factor Is Mandatory To Rescue Neuroectodermic Cells from Apoptosis
ABSTRACT Hirschsprung's disease (HSCR), a frequent developmental defect of the enteric nervous system is due to loss-of-function… 
2000
2000
Abrogation of Nerve Growth Factor-induced Terminal Differentiation by ret Oncogene Involves Perturbation of Nuclear Translocation of ERK*
Oncogenic variants of the receptor tyrosine kinase, Ret, cause formation of tumors of neuroendocrine derivation in the multiple… 
1999
1999
Induction of glial cell line-derived neurotrophic factor receptor proteins in cerebral cortex and striatum after permanent middle cerebral artery occlusion in rats
1996
1996
A potential pathogenetic mechanism for multiple endocrine neoplasia type 2 syndromes involves ret-induced impairment of terminal differentiation of neuroepithelial cells.
Germ-line missense mutations of the receptor-like tyrosine kinase ret are the causative genetic event of the multiple endocrine… 
1990
1990
Standard maps of chromosome 10
To achieve consensus more exact definitions of genetical maps are required, of which standard, comprehensive and skeletal might… 
1990
1990
Oncogenicity of the ret transforming gene in MMTV/ret transgenic mice.
We have successfully produced transgenic mice that carry the ret oncogene driven by a mouse mammary tumor virus promoter/enhancer… 
1989
1989
Presence of Aberrant Transcripts of ret Proto‐oncogene in a Human Papillary Thyroid Carcinoma Cell Line
In a papillary thyroid carcinoma cell line, TPC‐1, we found transcripts hybridizing to ret proto‐oncogene (proto‐ret) cDNA probes… 
Highly Cited
1983
Highly Cited
1983
The subcellular localization of rat photoreceptor-specific antigens
SummaryThe subcellular localization of three photoreceptor antigens (RET-P1, rhodopsin and RET-P2) has been studied by electron… 
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