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OPC 31260

Known as: Opc-31260 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
cAMP plays a major role in cystogenesis. Recent in vitro studies suggested that cAMP stimulates B-Raf/ERK activation and… Expand
Highly Cited
2003
Highly Cited
2003
In the present study, two experiments were performed to investigate the influence of OPC-31260 on experimentally induced… Expand
Highly Cited
1998
Highly Cited
1998
The pharmacological profile and the acute and chronic aquaretic effects of OPC-41061, a novel nonpeptide human arginine… Expand
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Highly Cited
1997
Highly Cited
1997
The present study was undertaken to determine whether the non-peptide V2 arginine vasopressin (AVP) antagonist 5-dimethylamino- 1… Expand
Highly Cited
1994
Highly Cited
1994
Rapid right ventricular pacing could induce congestive heart failure in conscious dogs with significant increase in plasma… Expand
Highly Cited
1994
Highly Cited
1994
The present study was undertaken to determine whether a non-peptide arginine vasopressin (AVP) antagonist [5-dimethylamino-1-(4… Expand
Highly Cited
1994
Highly Cited
1994
To examine whether expression and distribution of aquaporin of collecting duct (AQP-CD) are regulated by vasopressin V2 receptor… Expand
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Highly Cited
1993
Highly Cited
1993
Solute-free water diuretics (aquaretics) by antagonizing hydrosmotic vasopressin receptors (V2) may be useful in treating water… Expand
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Highly Cited
1993
Highly Cited
1993
The present study was undertaken to determine whether the non-peptide V2 antidiuretic hormone (ADH) antagonist 5-dimethylamino-1… Expand
Highly Cited
1992
Highly Cited
1992
1 OPC‐31260, a benzazepine derivative, has been studied for its ability to antagonize the binding of arginine vasopressin (AVP… Expand