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Reduced thirst after water deprivation in healthy elderly men.
To determine whether responses to dehydration are altered with age, we investigated the thirst, fluid and electrolyte responses, and hormonal responses to 24 hours of water deprivation in sevenExpand
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Aging and disturbances of thirst and fluid balance.
Fluid and electrolyte homeostasis depend on a balance between the intake and output of water. Aging is characterized by reduced homeostatic capacity. Changes in the control of both water intake andExpand
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Reduced osmotic thirst in healthy elderly men.
In response to water deprivation or heat stress, healthy elderly men experience reduced thirst compared with a young control group. Because water deprivation and heat stress produce hypertonicity asExpand
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Altered water excretion in healthy elderly men.
The renal and vasopressin (AVP) response to a standard oral water load (20 ml/kg) was examined in a group of water-replete healthy elderly men (n = 6). Two groups, respectively, of water-replete andExpand
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Effect of aging on regional cerebral blood flow responses associated with osmotic thirst and its satiation by water drinking: A PET study
Levels of thirst and ad libitum drinking decrease with advancing age, making older people vulnerable to dehydration. This study investigated age-related changes in brain responses to thirst andExpand
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Osmotic thirst and vasopressin release in humans: a double-blind crossover study.
Thirst is a subjective sensation. Therefore to investigate further the nature, intensity, and specificity of osmotic thirst, we studied the effects of double-blind infusions of hypertonic (0.45 M)Expand
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Body fluid changes, thirst and drinking in man during free access to water
To investigate whether human thirst and drinking during ad lib access to water occur in response to body fluid deficits, we obtained blood samples and visual analog scale thirst ratings from fiveExpand
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Interaction between atrial natriuretic peptide and the renin angiotensin aldosterone system. Endogenous antagonists.
The biologic actions of the cardiac peptide hormone atrial natriuretic peptide (ANP) of vasorelaxation, diuresis and natriuresis, suppression of aldosterone, vasopressin release, and thirst are theExpand
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Effects of drinking on thirst and vasopressin in dehydrated elderly men.
Inhibition of dehydration-induced arginine vasopressin (AVP) secretion and thirst depends on removal of osmotic and hemodynamic stimuli as well as on preabsorptive oropharyngeal factors that reduceExpand
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Cortical activation and lamina terminalis functional connectivity during thirst and drinking in humans.
The pattern of regional brain activation in humans during thirst associated with dehydration, increased blood osmolality, and decreased blood volume is not known. Furthermore, there is littleExpand
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