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Nuclear Receptor Coactivator 4

Known as: Androgen Receptor-Associated Protein of 70 kDa, RET Activating Protein ELE1, Androgen Receptor-Specific Coactivator 
Nuclear receptor coactivator 4 (579 aa, ~66 kDa) is encoded by the human NCOA4 gene. This protein plays a role in the modulation of androgen receptor… 
National Institutes of Health

Related topics

Related topics

5 relations
Genes, RegulatorNCOA4 geneTranscription CoactivatorTranscriptional Activation

Papers overview

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Highly Cited
2018
Highly Cited
2018
Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
It is not clear to what extent starvation-induced autophagy affects the proteome on a global scale and whether it is selective… 
Highly Cited
2012
Highly Cited
2012
Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis
One of the central goals of human genetics is to discover the genes and pathways driving human traits. To date, most of the… 
Highly Cited
2010
Highly Cited
2010
Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)
Bone marrow-derived mesenchymal stem cells (MSCs) are known to specifically migrate to and engraft at tumour sites. Understanding… 
Review
2004
Review
2004
Expression and function of androgen receptor coactivators in prostate cancer
Highly Cited
2001
Highly Cited
2001
Hormone Status Selects for Spontaneous Somatic Androgen Receptor Variants That Demonstrate Specific Ligand and Cofactor Dependent Activities in Autochthonous Prostate Cancer*
We have used the autochthonoustransgenic adenocarcinoma of mouseprostate (TRAMP) model to investigate the relationship between… 
Highly Cited
2000
Highly Cited
2000
Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells.
Although mutations of the breast cancer susceptibility gene 1 (BRCA1) may play important roles in breast and prostate cancers… 
Highly Cited
1999
Highly Cited
1999
Cloning and Characterization of Human Prostate Coactivator ARA54, a Novel Protein That Associates with the Androgen Receptor*
Androgen receptor (AR) is a member of the steroid receptor superfamily that may require coactivators for proper or maximal… 
Highly Cited
1999
Highly Cited
1999
Isolation and Characterization of ARA160 as the First Androgen Receptor N-terminal-associated Coactivator in Human Prostate Cells*
The androgen receptor (AR) is a member of the steroid receptor superfamily that may require coactivators for proper or maximal… 
Highly Cited
1999
Highly Cited
1999
Resveratrol inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells.
Androgens via their receptor (AR) may play a role in prostate cancer etiology. This study focuses on the inhibitory effects of… 
Review
1997
Review
1997
Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.
Steroid/thyroid hormone receptors are ligand-dependent transcription factors that regulate diverse aspects of growth, development… 
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