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Nuclear Receptor Coactivator 4

Known as: Androgen Receptor-Associated Protein of 70 kDa, RET Activating Protein ELE1, Androgen Receptor-Specific Coactivator 
Nuclear receptor coactivator 4 (579 aa, ~66 kDa) is encoded by the human NCOA4 gene. This protein plays a role in the modulation of androgen receptor… 
National Institutes of Health

Related topics

Related topics

5 relations
Genes, RegulatorNCOA4 geneTranscription CoactivatorTranscriptional Activation

Papers overview

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2013
2013
Investigation of the Relationship Between Prostate Cancer and MSMB and NCOA4 Genetic Variants and Protein Expression
Two genome‐wide association studies (GWAS) identified the β‐microseminoprotein (MSMB) promoter SNP, rs10993994:C>T, as… 
2006
2006
Myostatin negatively regulates the expression of the steroid receptor co‐factor ARA70
Myostatin is a transforming growth factor‐β (TGF‐β) superfamily member and a key negative regulator of embryonic and postnatal… 
2003
2003
Loss of coordinated androgen regulation in nonmalignant ovarian epithelial cells with BRCA1/2 mutations and ovarian cancer cells.
Epidemiological studies have implicated androgens in the etiology/progression of epithelial ovarian cancer. Because normal and… 
2002
2002
Mutations in the Helix 3 Region of the Androgen Receptor Abrogate ARA70 Promotion of 17β-Estradiol-induced Androgen Receptor Transactivation*
The influence of estrogen on the development of the male reproductive system may be interrupted in a subset of partial androgen… 
Review
2001
Review
2001
Identification and characterization of androgen receptor associated coregulators in prostate cancer cells.
The androgen receptor (AR) is a member of the nuclear receptor (NR) superfamily that mediates the effects of androgens on target… 
2001
2001
RET rearrangements in radiation-induced papillary thyroid carcinomas: high prevalence of topoisomerase I sites at breakpoints and microhomology-mediated end joining in ELE1 and RET chimeric genes.
Children exposed to radioactive iodine after the Chernobyl reactor accident frequently developed papillary thyroid carcinomas… 
Highly Cited
2000
Highly Cited
2000
Expression of androgen receptor coregulatory proteins in prostate cancer and stromal‐cell culture models
Androgen receptor (AR) transcriptional activity is modulated by cofactor proteins. They act as costimulators, corepressors, or… 
Highly Cited
2000
Highly Cited
2000
RET receptor expression in thyroid follicular epithelial cell-derived tumors.
The RET proto-oncogene encodes a receptor tyrosine kinase for transforming growth factor-beta-related neurotrophic factors, which… 
Review
2000
Review
2000
Outlook for Biomass Ethanol Production and Demand by Joseph DiPardo
The production of ethanol from corn is a mature technology that is not likely to see significant reductions in production costs… 
Highly Cited
1997
Highly Cited
1997
Comparison of the breakpoint regions of ELE1 and RET genes involved in the generation of RET/PTC3 oncogene in sporadic and in radiation-associated papillary thyroid carcinomas.
The RET/PTC3 oncogene is an activated form of the RET protooncogene, which is frequently rearranged in papillary thyroid… 
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