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Nuclear Receptor Coactivator 4

Known as: Androgen Receptor-Associated Protein of 70 kDa, RET Activating Protein ELE1, Androgen Receptor-Specific Coactivator 
Nuclear receptor coactivator 4 (579 aa, ~66 kDa) is encoded by the human NCOA4 gene. This protein plays a role in the modulation of androgen receptor… Expand
National Institutes of Health

Related topics

Related topics

5 relations
Genes, RegulatorNCOA4 geneTranscription CoactivatorTranscriptional Activation
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Autophagy promotes ferroptosis by degradation of ferritin
ABSTRACT Macroautophagy/autophagy is an evolutionarily conserved degradation pathway that maintains homeostasis. Ferroptosis, a… Expand
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Highly Cited
2014
Highly Cited
2014
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Autophagy, the process by which proteins and organelles are sequestered in double-membrane structures called autophagosomes and… Expand
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Highly Cited
2010
Highly Cited
2010
Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)
Bone marrow-derived mesenchymal stem cells (MSCs) are known to specifically migrate to and engraft at tumour sites. Understanding… Expand
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Review
2004
Review
2004
Expression and function of androgen receptor coactivators in prostate cancer
Human androgen receptor (AR) associates with coactivator or corepressor proteins that modulate its activation in the presence of… Expand
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Highly Cited
2001
Highly Cited
2001
Random Flow Generation Technique for Large Eddy Simulations and Particle-Dynamics Modeling
A random flow generation (RFG) technique is presented, which can be used for initial/ inlet boundary generation in LES (Large… Expand
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Highly Cited
1999
Highly Cited
1999
Cloning and Characterization of Human Prostate Coactivator ARA54, a Novel Protein That Associates with the Androgen Receptor*
Androgen receptor (AR) is a member of the steroid receptor superfamily that may require coactivators for proper or maximal… Expand
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Highly Cited
1999
Highly Cited
1999
From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells.
Overexpression of the HER2/Neu protooncogene has been linked to the progression of breast cancer. Here we demonstrate that the… Expand
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Highly Cited
1999
Highly Cited
1999
Identification of ARA70 as a Ligand-enhanced Coactivator for the Peroxisome Proliferator-activated Receptor γ*
In an effort to understand transcriptional regulation by the peroxisome proliferator-activated receptor γ (PPARγ), we have… Expand
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Review
1997
Review
1997
Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.
Steroid/thyroid hormone receptors are ligand-dependent transcription factors that regulate diverse aspects of growth, development… Expand
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Highly Cited
1996
Highly Cited
1996
Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.
The androgen receptor (AR) is a member of the steroid receptor superfamily that plays an important role in male sexual… Expand
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