FAQ

Nuclear Receptor Coactivator 4

Known as: Androgen Receptor-Associated Protein of 70 kDa, RET Activating Protein ELE1, Androgen Receptor-Specific Coactivator 
Nuclear receptor coactivator 4 (579 aa, ~66 kDa) is encoded by the human NCOA4 gene. This protein plays a role in the modulation of androgen receptor… (More)

Topic mentions per year

Topic mentions per year

1975-2018
05101519752018

Related topics

Related topics

5 relations
Genes, RegulatorNCOA4 geneTranscription CoactivatorTranscriptional Activation
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Related mentions per year

Related mentions per year

1964-2018
1960198020002020
Nuclear Receptor Coactivator 4
Genes, Regulator
Transcriptional Regulation
NCOA4 gene
Transcription Coactivator
Transcriptional Activation

Papers overview

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Highly Cited
2014
Highly Cited
2014
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
Autophagy, the process by which proteins and organelles are sequestered in double-membrane structures called autophagosomes and… (More)
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Highly Cited
2010
Highly Cited
2010
Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)
Bone marrow-derived mesenchymal stem cells (MSCs) are known to specifically migrate to and engraft at tumour sites. Understanding… (More)
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Highly Cited
2002
Highly Cited
2002
Proteasome activity is required for androgen receptor transcriptional activity via regulation of androgen receptor nuclear translocation and interaction with coregulators in prostate cancer cells.
Upon binding to androgen, the androgen receptor (AR) can translocate into the nucleus and bind to androgen response element(s) to… (More)
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Highly Cited
1999
Highly Cited
1999
From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells.
Overexpression of the HER2/Neu protooncogene has been linked to the progression of breast cancer. Here we demonstrate that the… (More)
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1999
1999
Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells.
The androgen receptor (AR) is a member of the steroid receptor superfamily that may require coactivators for proper or maximal… (More)
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1999
1999
Differential induction of androgen receptor transactivation by different androgen receptor coactivators in human prostate cancer DU145 cells.
Recently identified androgen receptor (AR) coactivators were used in this study to determine whether the specificity of sex… (More)
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Highly Cited
1998
Highly Cited
1998
From estrogen to androgen receptor: a new pathway for sex hormones in prostate.
While all three coactivators ARA70, steroid receptor coactivator 1, and RAC3/ACTR can enhance androgen receptor (AR… (More)
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Highly Cited
1998
Highly Cited
1998
Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells.
Although hormone therapy with antiandrogens has been widely used for the treatment of prostate cancer, some antiandrogens may act… (More)
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Highly Cited
1996
Highly Cited
1996
Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.
  • S D Yeh, C. Chang
  • Proceedings of the National Academy of Sciences…
  • 1996
The androgen receptor (AR) is a member of the steroid receptor superfamily that plays an important role in male sexual… (More)
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Highly Cited
1994
Highly Cited
1994
Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma.
The RET proto-oncogene encodes a transmembrane receptor of the tyrosine kinase family and has frequently been found activated in… (More)
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