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Neurotensin/Neuromedin N, Human

Known as: Pro-Neurotensin, Pro-NT/N, Neurotensin/Neuromedin 
Neurotensin/neuromedin N (170 aa, ~20 kDa) is encoded by the human NTS gene. This protein may play a role in both the digestion of fat in the gut and… 
National Institutes of Health

Related topics

Related topics

4 relations
G Protein-Coupled Receptor SignalingMetabolismNTS geneSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Safety of the intravenous administration of neurotensin-polyplex nanoparticles in BALB/c mice.
2009
2009
Activation of NTS A2a adenosine receptors differentially resets baroreflex control of renal vs. adrenal sympathetic nerve activity.
The role of nucleus of solitary tract (NTS) A(2a) adenosine receptors in baroreflex mechanisms is controversial. Stimulation of… 
2004
2004
Species differences in brain pre-pro-neurotensin/neuromedin N mRNA distribution: the expression pattern in mice resembles more closely that of primates than rats.
2000
2000
Immunohistochemical evidence for the involvement of protein convertases 5A and 2 in the processing of pro‐neurotensin in rat brain
The neuropeptides/neurotransmitters neurotensin (NT) and neuromedin (NN) are synthesized by endoproteolytic cleavage of a common… 
1999
1999
Protein 7B2 is essential for the targeting and activation of PC2 into the regulated secretory pathway of rMTC 6-23 cells.
Among the prohormone convertases, PC2 is unique in that it specifically binds to the neuroendocrine-specific protein 7B2 in the… 
1998
1998
PC5-A-mediated Processing of Pro-neurotensin in Early Compartments of the Regulated Secretory Pathway of PC5-transfected PC12 Cells*
Among the members of the proprotein convertase (PC) family, PC1 and PC2 have well established roles as prohormone convertases… 
1998
1998
Pro-neurotensin/neuromedin N expression and processing in human colon cancer cell lines.
The regulatory peptide neurotensin NT has been proposed to exert an autocrine trophic effect on human colon cancers. In the… 
Highly Cited
1996
Highly Cited
1996
Evidence That PC2 Is the Endogenous Pro-neurotensin Convertase in rMTC 6-23 Cells and That PC1- and PC2-transfected PC12 Cells Differentially Process Pro-neurotensin (*)
The neuropeptide precursor proneurotensin/neuromedin N (pro-NT/NN) is mainly expressed and differentially processed in the brain… 
1994
1994
Neurotensin and neuromedin N undergo distinct catabolic processes in murine astrocytes and primary cultured neurons.
We examined the occurrence of various endopeptidases and exopeptidases and their subcellular partition within soluble and… 
1990
1990
The effect of acute haloperidol treatment on brain proneurotensin mRNA: in situ hybridization analyses using a novel fluorescence detection procedure.
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