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NTRK1 wt Allele
Known as:
TRK
, Neurotrophic Tyrosine Kinase, Receptor, Type 1 wt Allele
, MTC
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Human NTRK1 wild-type allele is located within 1q21-q22 and is approximately 21 kb in length. This allele, which encodes high affinity nerve growth…
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National Institutes of Health
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Related topics
Related topics
19 relations
1q21-q22
Apoptosis
Familial medullary thyroid carcinoma
High Affinity Nerve Growth Factor Receptor, human
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Broader (1)
NTRK1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
A Novel p75 Neurotrophin Receptor-Related Protein, NRH2, Regulates Nerve Growth Factor Binding to the TrkA Receptor
S. Murray
,
Pilar Pérez
,
Ramee Lee
,
B. Hempstead
,
M. Chao
Journal of Neuroscience
2004
Corpus ID: 8729586
Nerve growth factor (NGF) functions as a ligand for two receptors, the TrkA tyrosine kinase receptor and the p75 neurotrophin…
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Highly Cited
2003
Highly Cited
2003
Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat
S. Galoyan
,
J. Petruska
,
L. Mendell
European Journal of Neuroscience
2003
Corpus ID: 25032438
We investigated the regulation by nerve growth factor of the response of sensory neurons to noxious heat (>43 °C). In dissociated…
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Highly Cited
2002
Highly Cited
2002
FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling
Wenhua Zheng
,
S. Kar
,
R. Quirion
Journal of Neurochemistry
2002
Corpus ID: 40338625
We report that the Forkhead family of transcription factors, FKHRL1, FKHR and AFX are novel components of neurotrophin receptor…
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Highly Cited
2002
Highly Cited
2002
Expression of the neurotrophin receptor TrkA down-regulates expression and function of angiogenic stimulators in SH-SY5Y neuroblastoma cells.
A. Eggert
,
M. Grotzer
,
N. Ikegaki
,
Xing-ge Liu
,
A. Evans
,
G. Brodeur
Cancer Research
2002
Corpus ID: 8673769
Angiogenesis is essential for tumor growth and metastasis and depends on the production of angiogenic factors. Mechanisms…
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Highly Cited
1997
Highly Cited
1997
Nerve growth factor receptor trkA is down‐regulated during postnatal development by a subset of dorsal root ganglion neurons
D. Molliver
,
W. Snider
The Journal of comparative neurology
1997
Corpus ID: 29846543
Nerve growth factor (NGF), signaling through its receptor tyrosine kinase, TrkA, is required for the survival of all small and…
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Highly Cited
1996
Highly Cited
1996
Expression of trKB neurotrophin receptor during T cell development. Role of brain derived neurotrophic factor in immature thymocyte survival.
M. Maroder
,
D. Bellavia
,
+8 authors
Isabella Screpanti
Journal of Immunology
1996
Corpus ID: 45711839
The relationships between the nervous and the immune systems raise the question of whether neurotrophic factors, in addition to…
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Highly Cited
1995
Highly Cited
1995
Transfection of TRK-A into human neuroblastoma cells restores their ability to differentiate in response to nerve growth factor.
E. Lavenius
,
C. Gestblom
,
I. Johansson
,
E. Nånberg
,
Sven Påhlman
Cell growth & differentiation : the molecular…
1995
Corpus ID: 29183679
Human neuroblastoma cell lines frequently express the TRK-A proto-oncogene and bind nerve growth factor (NGF) but do not…
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Highly Cited
1995
Highly Cited
1995
Interaction with TrkA Immobilizes gp75 in the High Affinity Nerve Growth Factor Receptor Complex (*)
D. E. Wolf
,
C. McKinnon
,
M. Daou
,
Robert M. Stephens
,
D. Kaplan
,
A. Ross
Journal of Biological Chemistry
1995
Corpus ID: 27852715
It has been proposed that the high affinity nerve growth factor (NGF) receptor required for NGF response is a complex of two…
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Highly Cited
1993
Highly Cited
1993
Tissue-specific alternative splicing generates two isoforms of the trkA receptor.
Philip A. Barker
,
Catherine Lomen-Hoerth
,
E. Gensch
,
Susan 0. Meakin
,
David J. Glass
,
Eric M. Shooter
Journal of Biological Chemistry
1993
Corpus ID: 35105525
Highly Cited
1993
Highly Cited
1993
Regulation of expression of mRNAs encoding the nerve growth factor receptors p75 and trkA in developing sensory neurons.
S. Wyatt
,
A. Davies
Development
1993
Corpus ID: 17398063
We have used a quantitative reverse transcription/polymerase chain reaction amplification technique to study the regulation of…
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