Skip to search formSkip to main contentSkip to account menu

NTRK1 wt Allele

Known as: TRK, Neurotrophic Tyrosine Kinase, Receptor, Type 1 wt Allele, MTC 
Human NTRK1 wild-type allele is located within 1q21-q22 and is approximately 21 kb in length. This allele, which encodes high affinity nerve growth… 
National Institutes of Health

Related topics

Related topics

19 relations
1q21-q22ApoptosisFamilial medullary thyroid carcinomaHigh Affinity Nerve Growth Factor Receptor, human

Broader (1)

NTRK1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
A Novel p75 Neurotrophin Receptor-Related Protein, NRH2, Regulates Nerve Growth Factor Binding to the TrkA Receptor
Nerve growth factor (NGF) functions as a ligand for two receptors, the TrkA tyrosine kinase receptor and the p75 neurotrophin… 
Highly Cited
2003
Highly Cited
2003
Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat
We investigated the regulation by nerve growth factor of the response of sensory neurons to noxious heat (>43 °C). In dissociated… 
Highly Cited
2002
Highly Cited
2002
FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling
We report that the Forkhead family of transcription factors, FKHRL1, FKHR and AFX are novel components of neurotrophin receptor… 
Highly Cited
2002
Highly Cited
2002
Expression of the neurotrophin receptor TrkA down-regulates expression and function of angiogenic stimulators in SH-SY5Y neuroblastoma cells.
Angiogenesis is essential for tumor growth and metastasis and depends on the production of angiogenic factors. Mechanisms… 
Highly Cited
1997
Highly Cited
1997
Nerve growth factor receptor trkA is down‐regulated during postnatal development by a subset of dorsal root ganglion neurons
Nerve growth factor (NGF), signaling through its receptor tyrosine kinase, TrkA, is required for the survival of all small and… 
Highly Cited
1996
Highly Cited
1996
Expression of trKB neurotrophin receptor during T cell development. Role of brain derived neurotrophic factor in immature thymocyte survival.
The relationships between the nervous and the immune systems raise the question of whether neurotrophic factors, in addition to… 
Highly Cited
1995
Highly Cited
1995
Transfection of TRK-A into human neuroblastoma cells restores their ability to differentiate in response to nerve growth factor.
Human neuroblastoma cell lines frequently express the TRK-A proto-oncogene and bind nerve growth factor (NGF) but do not… 
Highly Cited
1995
Highly Cited
1995
Interaction with TrkA Immobilizes gp75 in the High Affinity Nerve Growth Factor Receptor Complex (*)
It has been proposed that the high affinity nerve growth factor (NGF) receptor required for NGF response is a complex of two… 
Highly Cited
1993
Highly Cited
1993
Tissue-specific alternative splicing generates two isoforms of the trkA receptor.
Highly Cited
1993
Highly Cited
1993
Regulation of expression of mRNAs encoding the nerve growth factor receptors p75 and trkA in developing sensory neurons.
We have used a quantitative reverse transcription/polymerase chain reaction amplification technique to study the regulation of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)