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NTRK1 gene

Known as: high affinity nerve growth factor receptor, TYROSINE KINASE RECEPTOR, TYROSINE KINASE RECEPTOR A 
This gene is involved in cellular differentiation and neurotrophic functions.
National Institutes of Health

Related topics

Related topics

17 relations
Familial medullary thyroid carcinomaHigh Affinity Nerve Growth Factor Receptor Isoform TrkA-III, humanHigh Affinity Nerve Growth Factor Receptor, humanLigand Binding

Narrower (2)

NTRK1 wt AlleleTFG gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
p62 serves as a shuttling factor for TrkA interaction with the proteasome.
Highly Cited
2004
Highly Cited
2004
A Novel p75 Neurotrophin Receptor-Related Protein, NRH2, Regulates Nerve Growth Factor Binding to the TrkA Receptor
Nerve growth factor (NGF) functions as a ligand for two receptors, the TrkA tyrosine kinase receptor and the p75 neurotrophin… 
Highly Cited
2004
Highly Cited
2004
Substance P expression in TRPV1 and trkA-positive dorsal root ganglion neurons innervating the mouse lung
Highly Cited
2003
Highly Cited
2003
Association of the Atypical Protein Kinase C-interacting Protein p62/ZIP with Nerve Growth Factor Receptor TrkA Regulates Receptor Trafficking and Erk5 Signaling*
Previous work demonstrated an essential role for the atypical protein kinase C interacting protein, p62, in neurotrophin survival… 
Highly Cited
2001
Highly Cited
2001
Down‐regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease
Recent studies indicate that trkA expression is reduced in end‐stage Alzheimer's disease (AD). However, understanding the… 
Highly Cited
1997
Highly Cited
1997
Nerve growth factor receptor trkA is down‐regulated during postnatal development by a subset of dorsal root ganglion neurons
Nerve growth factor (NGF), signaling through its receptor tyrosine kinase, TrkA, is required for the survival of all small and… 
1997
1997
Transient Association of the Phosphotyrosine Phosphatase SHP‐2 with TrkA Is Induced by Nerve Growth Factor
Abstract: Nerve growth factor (NGF) treatment of rat PC12 pheochromocytoma cells results in an increase in the tyrosine… 
Highly Cited
1995
Highly Cited
1995
Interaction with TrkA Immobilizes gp75 in the High Affinity Nerve Growth Factor Receptor Complex (*)
It has been proposed that the high affinity nerve growth factor (NGF) receptor required for NGF response is a complex of two… 
Highly Cited
1995
Highly Cited
1995
Selective Regulation of TrkA and TrkB Receptors by Retinoic Acid and Interferon-γ in Human Neuroblastoma Cell Lines (*)
Trk receptors are a family of genes implicated in the survival, differentiation, and growth of certain neurons and tumors of the… 
1993
1993
Ectopic trkA expression mediates a NGF survival response in NGF- independent sensory neurons but not in parasympathetic neurons
We have investigated the role of trkA, the tyrosine kinase NGF receptor, in mediating the survival response of embryonic neurons… 
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