High Affinity Nerve Growth Factor Receptor, human

Known as: Trk-A, Nerve Growth Factor Receptor Type 1, Tropomyosin-Related Kinase A 
High affinity nerve growth factor receptor (796 aa, ~87 kDa) is encoded by the human NTRK1 gene. This protein is involved in tyrosine phosphorylation… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Tyrosine kinase receptors represent targets of great interest for cancer therapy. Here we show, for the first time, the… (More)
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Highly Cited
2010
Highly Cited
2010
Neurons of the peripheral nervous system have long been known to require survival factors to prevent their death during… (More)
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Highly Cited
1996
Highly Cited
1996
Oncogenic rearrangements of RET and NTRK1 proto-oncogenes are frequently detected in papillary thyroid carcinomas. Several… (More)
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1995
1995
Nerve growth factor-beta (NGF beta) and a NGF beta-immunoreactive protein derived from human prostatic stromal cell secretory… (More)
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1995
1995
It has been proposed that the high affinity nerve growth factor (NGF) receptor required for NGF response is a complex of two… (More)
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1995
1995
Neurotrophins initiate their biological effects by activating members of the trk tyrosine kinase subfamily. The extracellular… (More)
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1993
1993
Two anti-nerve growth factor receptor (LNGFR or p75NGFR) antibodies, Me20.4 and Me8211, label stromal cells with dendritic… (More)
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Highly Cited
1991
Highly Cited
1991
Two classes of receptors with distinct affinities for nerve growth factor (NGF) have been identified. The low affinity receptor… (More)
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Highly Cited
1991
Highly Cited
1991
The product of the trk proto-oncogene encodes a receptor for nerve growth factor (NGF). Here we show that NGF is a powerful… (More)
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Highly Cited
1991
Highly Cited
1991
We report the isolation and molecular characterization of trkC, a new member of the trk family of tyrosine protein kinase genes… (More)
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