Skip to search formSkip to main contentSkip to account menu

NOTCH1 wt Allele

Known as: Notch Homolog 1, Translocation-Associated Gene, Notch 1 wt Allele, hN1 
Human NOTCH1 wild-type allele is located in the vicinity of 9q34.3 and is approximately 51 kb in length. This allele, which encodes neurogenic locus… 
National Institutes of Health

Related topics

Related topics

16 relations
9q34.3ApoptosisCell Differentiation processCell Fate Control

Broader (1)

NOTCH1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
MiR-139-5p reverses CD44+/CD133+-associated multidrug resistance by downregulating NOTCH1 in colorectal carcinoma cells
MiRNAs may promote or inhibit tumor recurrence and drug resistance. MiR-139-5p is reportedly downregulated in colorectal cancer… 
2014
2014
14q deletions are associated with trisomy 12, NOTCH1 mutations and unmutated IGHV genes in chronic lymphocytic leukemia and small lymphocytic lymphoma
Deletions of the long arm of chromosome 14 [del(14q)] are rare but recurrently observed in mature B‐cell neoplasms, particularly… 
2014
2014
Notch1 increases Snail expression under high reactive oxygen species conditions in hepatocellular carcinoma cells
Abstract Notch1 and reactive oxygen species (ROS) modulate important pathways associated with tumor development and progression… 
2013
2013
The Different Role of Notch1 and Notch2 in Astrocytic Gliomas
It is well known that Notch signaling plays either oncogenic or tumor suppressive role in a variety of tumors, depending on the… 
2013
2013
Analysis of gene expression in wild‐type and Notch1 mutant retinal cells by single cell profiling
Background: The vertebrate retina comprises sensory neurons, the photoreceptors, as well as many other types of neurons and one… 
2012
2012
Cancer Stem Cell and Embryonic Development-Associated Molecules Contribute to Prognostic Significance in Ovarian Cancer
Objectives Embryonic molecules and cancer stem cell signaling resemble each other, and they organize cancer modality. We… 
2011
2011
Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma
The tumor suppressor p53 is a key prognostic factor in hepatocellular carcinoma (HCC), yet only 35% of grade III tumors exhibit… 
2011
2011
Another NOTCH for Cancer
Next-generation sequencing reveals NOTCH1 as an important tumor suppressor gene in head and neck cancer. Squamous cell carcinomas… 
2010
2010
NOTCH mutations as prognostic markers in T-ALL
Risk stratification plays a fundamental role in the treatment of acute lymphoblastic leukemia (ALL). Thus, patients harboring… 
2007
2007
Activating Notch1 mutations are an early event in T-cell malignancy of Ikaros point mutant Plastic/+ mice.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)