NOTCH1 gene

Known as: TRANSLOCATION-ASSOCIATED NOTCH HOMOLOG, Notch 1 Gene, notch 1 
This gene is involved in intercellular signal transduction that plays a key role in development.
National Institutes of Health

Papers overview

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2012
2012
Sorghum, an ancient old-world cereal grass, is the dietary staple of over 500 million people in more than 30 countries in the… (More)
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Highly Cited
2011
Highly Cited
2011
Chronic lymphocytic leukaemia (CLL), the most frequent leukaemia in adults in Western countries, is a heterogeneous disease with… (More)
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2010
2010
UNLABELLED One of the serious sequelae of chronic hepatitis B virus (HBV) infection is hepatocellular carcinoma (HCC). Among all… (More)
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Highly Cited
2008
Highly Cited
2008
The Notch receptor mediates cell fate decision in multiple organs. In the current work we tested the hypothesis that Nkx2.5 is a… (More)
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Highly Cited
2007
Highly Cited
2007
Activating mutations in the NOTCH1 gene have been found in about 60% of patients with T-cell acute lymphoblastic leukemia (T-ALL… (More)
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Review
2006
Review
2006
The chromosomal translocation t(7;9) in human T-cell acute lymphoblastic leukaemia (T-ALL) results in deregulated expression of a… (More)
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Highly Cited
2005
Highly Cited
2005
Protein kinase B (PKB) or Akt is one of several second messenger kinases that are activated by cell attachment and growth factor… (More)
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Highly Cited
2004
Highly Cited
2004
Signaling through the Notch1 receptor is essential for T cell development in the thymus. Stromal OP9 cells ectopically expressing… (More)
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Highly Cited
2001
Highly Cited
2001
We have recently reported that Notch 1, a member of the Notch multigene family, is essential for the development of murine T… (More)
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Highly Cited
1997
Highly Cited
1997
Approximately 10% of cases of Alzheimer's disease are familial and associated with autosomal dominant inheritance of mutations in… (More)
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