NKX2-5 gene

Known as: NKX2.5, MOUSE, HOMOLOG OF, CARDIAC-SPECIFIC HOMEOBOX 1, CSX 
This gene plays a role in both transcriptional regulation and heart development.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
0204019952017

Papers overview

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Highly Cited
2011
Highly Cited
2011
NKX2-5 is expressed in the heart throughout life. We targeted eGFP sequences to the NKX2-5 locus of human embryonic stem cells… (More)
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2009
2009
BACKGROUND Reports of somatic mutations found in hearts with cardiac septal defects have suggested that these mutations are… (More)
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2004
2004
NKX2-5 is a pivotal transcription factor in heart development. Previous studies on lymphocytic DNA provided evidence of familial… (More)
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2004
2004
NKX2-5 is a homeodomain-containing transcription factor important in cardiac development. Familial mutations in the NKX2-5 gene… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES We sought to examine the importance of mutations in the cardiac transcription factor gene NKX2-5 in patients with an… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES The purpose of this study was to estimate the frequency of NKX2.5 mutations in specific cardiovascular anomalies and… (More)
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Highly Cited
2003
Highly Cited
2003
A cryptic chromosome rearrangement, t(5;14)(q35.1;q32.2), recently identified in pediatric acute lymphoblastic leukemia (ALL… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Recent reports have implicated mutations in the transcription factor NKX2.5 as a cause of tetralogy of Fallot (TOF… (More)
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Highly Cited
2000
Highly Cited
2000
Heterozygous mutations in the cardiac homeobox gene, NKX2-5, underlie familial cases of atrial septal defect (ASD) with severe… (More)
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Highly Cited
1998
Highly Cited
1998
Mutations in the gene encoding the homeobox transcription factor NKX2-5 were found to cause nonsyndromic, human congenital heart… (More)
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