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NKX2-5 gene

Known as: NKX2.5, MOUSE, HOMOLOG OF, CARDIAC-SPECIFIC HOMEOBOX 1, CSX 
This gene plays a role in both transcriptional regulation and heart development.
National Institutes of Health

Related topics

Related topics

9 relations
Cell Differentiation processHomeobox Protein Nkx-2.5, humanHomo sapiensNKX2-6 gene
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NKX2-5 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
The CRISPR-associated Csx1 protein of Pyrococcus furiosus is an adenosine-specific endoribonuclease.
Prokaryotes are frequently exposed to potentially harmful invasive nucleic acids from phages, plasmids, and transposons. One… Expand
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Highly Cited
2014
Highly Cited
2014
Neutrophils/Lymphocytes Ratio in Patients With Cardiac Syndrome X and Its Association With Carotid Intima–Media Thickness
Neutrophils and lymphocytes (N/L) ratio and carotid intima–media thickness (C-IMT) value have been studied as new predictors of… Expand
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Highly Cited
2013
Highly Cited
2013
Inflammation and microvascular dysfunction in cardiac syndrome X patients without conventional risk factors for coronary artery disease.
OBJECTIVES The aim of this study was to ascertain whether coronary microvascular dysfunction (CMD) and inflammation are related… Expand
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Highly Cited
2010
Highly Cited
2010
Genome-wide association study of PR interval
The electrocardiographic PR interval (or PQ interval) reflects atrial and atrioventricular nodal conduction, disturbances of… Expand
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Highly Cited
2008
Highly Cited
2008
Relation between stress-induced myocardial perfusion defects on cardiovascular magnetic resonance and coronary microvascular dysfunction in patients with cardiac syndrome X.
OBJECTIVES The purpose of this study was to investigate whether a direct relation can be demonstrated between myocardial… Expand
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Highly Cited
2007
Highly Cited
2007
Vascular endothelial function and circulating endothelial progenitor cells in patients with cardiac syndrome X
Background: Endothelial dysfunction and microvascular abnormalities have been reported in patients with cardiac syndrome X (CSX… Expand
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Highly Cited
2004
Highly Cited
2004
Novel NKX2-5 mutations in diseased heart tissues of patients with cardiac malformations.
NKX2-5 is a homeodomain-containing transcription factor important in cardiac development. Familial mutations in the NKX2-5 gene… Expand
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Highly Cited
2003
Highly Cited
2003
Chronic inflammation and increased arterial stiffness in patients with cardiac syndrome X.
AIMS Endothelial dysfunction and subangiographic atheroma have been reported in patients with cardiac syndrome X (CSX) but little… Expand
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Highly Cited
2003
Highly Cited
2003
Are five-view plain films of the cervical spine unreliable? A prospective evaluation in blunt trauma patients with altered mental status.
OBJECTIVES Clearing the cervical spine in a time-sensitive fashion is difficult. We hypothesized that admission computed… Expand
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Highly Cited
1999
Highly Cited
1999
Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways.
Heterozygous mutations in NKX2.5, a homeobox transcription factor, were reported to cause secundum atrial septal defects and… Expand
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