Skip to search formSkip to main contentSkip to account menu

NKX2-5 wt Allele

Known as: Tinman Paralog (Drosophila) Gene, HLHS2, CSX 
Human NKX2-5 wild-type allele is located in the vicinity of 5q34 and is approximately 3 kb in length. This allele, which encodes homeobox protein Nkx… 
National Institutes of Health

Related topics

Related topics

11 relations
5q34ALK PathwayCell Differentiation processHOP Pathway

Broader (1)

NKX2-5 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Establishment of Relational Model of Congenital Heart Disease Markers and GO Functional Analysis of the Association between Its Serum Markers and Susceptibility Genes
Purpose. The purpose of present study was to construct the best screening model of congenital heart disease serum markers and to… 
2013
2013
R25C mutation in the NKX2.5 gene in Italian patients affected with non-syndromic and syndromic congenital heart disease
Aims Heterozygous mutations in the transcription factor Nkx2.5 indicate a genetic cause for congenital heart diseases (CHDs) in… 
2011
2011
Ventricular noncompaction and absent thumbs in a newborn with tetrasomy 5q35.2‐5q35.3: An association with Hunter–McAlpine syndrome?
We report on an infant with tetrasomy of 5q35.2‐5q35.3, an interstitial triplication on one chromosome and normal complement on… 
2011
2011
Transactivation in Drosophila of Human Enhancers by Human Transcription Factors Involved in Congenital Heart Diseases
Background: The human transcription factors (TFs) GATA4, NKX2.5 and TBX5 form part of the core network necessary to build a human… 
2009
2009
The Derailment of Section 13(D) Liability after CSX v. Children's Investment Fund: An Argument for Maintaining the Beneficial Ownership Requirement for Section 13(D) Disclosure
2008
2008
Crystallization and preliminary X-ray analysis of the NKX2.5 homeodomain in complex with DNA.
As part of an effort to elucidate the molecular basis for the pathogenesis of NKX2.5 mutations in congenital heart disease using… 
2007
2007
RNA‐binding protein Csx1 is phosphorylated by LAMMER kinase, Lkh1, in response to oxidative stress in Schizosaccharomyces pombe
Review
2005
Review
2005
NKX2.5 and congenital heart defects: A population‐based study
Multiple animal studies have demonstrated the important role of NKX2.5, a homeobox transcription factor, in cardiogenesis [Komuro… 
2002
2002
Novel Point Mutation in the Cardiac Transcription Factor CSX / NKX 2 . 5 Associated With Congenital Heart Disease
Cardiogenic lineages originate from anterior lateral mesoderm soon after gastulation and develop into cardiac primordia that fuse… 
1995
1995
Assignment of cardiac homeobox gene CSX to human chromosome 5q34.
Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)