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Homeobox Protein Nkx-2.5, human

Known as: Cardiac-Specific Homeobox, Homeobox Protein NK-2 Homolog E, Homeobox Protein CSX 
Homeobox protein Nkx-2.5 (324 aa, ~35 kDa) is encoded by the human NKX2-5 gene. This protein plays a role in myocardial differentiation.
National Institutes of Health

Related topics

Related topics

14 relations
ALK PathwayCell NucleusDNA-Binding ProteinsGenes, Regulator
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Broader (1)

Homeobox Protein Nkx-2.5

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Novel and Highly Lethal NKX2.5 Missense Mutation in a Family With Sudden Death and Ventricular Arrhythmia
To date, several disease-related mutations in NKX2-5, a cardiac-specific homeobox gene, have been documented in patients with a… Expand
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2007
2007
Altered expression of early cardiac marker genes in circulating cells of patients with hypertrophic cardiomyopathy.
BACKGROUND Early cardiac marker genes, such as cardiac-specific homeobox (Csx/Nkx2.5), myocardin, homeodomain only protein, GATA4… Expand
Highly Cited
1993
Highly Cited
1993
Csx: a murine homeobox-containing gene specifically expressed in the developing heart.
  • I. Komuro, S. Izumo
  • Proceedings of the National Academy of Sciences…
  • 1993
    • Corpus ID: 24476441
The molecular control of the differentiation process depends in part on lineage-restricted transcription factors that regulate… Expand
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