FAQ

Homeobox Protein Nkx-2.5, human

Known as: Cardiac-Specific Homeobox, Homeobox Protein NK-2 Homolog E, Homeobox Protein CSX 
Homeobox protein Nkx-2.5 (324 aa, ~35 kDa) is encoded by the human NKX2-5 gene. This protein plays a role in myocardial differentiation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2014
0119932014

Related topics

Related topics

13 relations
Cell NucleusDNA-Binding ProteinsGenes, RegulatorHOP Pathway
(More)

Broader (1)

Homeobox Protein Nkx-2.5

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Homeobox Protein Nkx-2.5, human
Cell Nucleus
Heart
Transcriptional Activation
Transcriptional Regulation
dna binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Novel and Highly Lethal NKX2.5 Missense Mutation in a Family With Sudden Death and Ventricular Arrhythmia
To date, several disease-related mutations in NKX2-5, a cardiac-specific homeobox gene, have been documented in patients with a… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
2007
2007
Altered expression of early cardiac marker genes in circulating cells of patients with hypertrophic cardiomyopathy.
BACKGROUND Early cardiac marker genes, such as cardiac-specific homeobox (Csx/Nkx2.5), myocardin, homeodomain only protein, GATA4… (More)
Is this relevant?
2005
2005
Csx : A murine homeobox-containing gene specifically expressed in the developing heart ( cardiac development / transcription factor / tissue-specific gene expression / embryonic stem cell…
The molecular control of the differentiation process depends in part on lineage-restricted transcription factors that regulate… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1998
1998
Upregulation of the cardiac homeobox gene Nkx2-5 (CSX) in feline right ventricular pressure overload.
The recent characterization of the cardiac-specific homeobox gene Nkx2-5 (or CSX) and its detection in normal adult heart tissue… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
Csx: a murine homeobox-containing gene specifically expressed in the developing heart.
The molecular control of the differentiation process depends in part on lineage-restricted transcription factors that regulate… (More)
Is this relevant?