Homeobox Protein Nkx-2.5

Known as: Homeobox Transcription Factor Csx-Nkx2-5, Homeobox Transcription Factor Csx Nkx2 5, Transcription Factor Nkx-2.5 
A homeobox-containing transcription factor that functions in heart development. Mutations in the NKX2-5 gene are associated with ATRIAL SEPTAL… (More)
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
The main oncogenic driver in T-lymphoblastic leukemia is NOTCH1, which activates genes by forming chromatin-associated Notch… (More)
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Highly Cited
2013
Highly Cited
2013
The mammalian Sir2 ortholog Sirt1 plays an important role in metabolic regulation. However, the role of Sirt1 in the regulation… (More)
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Highly Cited
2011
Highly Cited
2011
Induced pluripotent stem cells (iPSCs) are generated from somatic cells by the transgenic expression of three transcription… (More)
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Review
2011
Review
2011
Reactive oxygen species (ROS) and cellular oxidative stress are involved in many physiological and pathophysiological processes… (More)
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Highly Cited
2009
Highly Cited
2009
Type 2 diabetes mellitus (T2DM) results from pancreatic beta cell failure in the setting of insulin resistance. Heterozygous… (More)
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Highly Cited
2008
Highly Cited
2008
MicroRNAs are noncoding RNAs that inhibit the expression of their targets in a sequence-specific manner and play crucial roles… (More)
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Highly Cited
2007
Highly Cited
2007
Somatic alterations in cellular DNA underlie almost all human cancers. The prospect of targeted therapies and the development of… (More)
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Highly Cited
2006
Highly Cited
2006
Leaf development in higher plants requires the specification of leaf initials at the flanks of a pluripotent structure termed the… (More)
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Review
2001
Review
2001
Pancreatic duodenal homeobox –1 is a transcription factor that is expressed in beta and δ cells of the islets of Langerhans and… (More)
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Review
2000
Review
2000
Homeobox genes play fundamental roles in development. They can be subdivided into several subfamilies, one of which is the LIM… (More)
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