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Homeobox Protein Nkx-2.5
Known as:
Homeobox Transcription Factor Csx-Nkx2-5
, Homeobox Transcription Factor Csx Nkx2 5
, Transcription Factor Nkx-2.5
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A homeobox-containing transcription factor that functions in heart development. Mutations in the NKX2-5 gene are associated with ATRIAL SEPTAL…
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National Institutes of Health
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9 relations
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Homeobox Protein Nkx-2.5, human
In Blood
Process of secretion
agonists
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Overexpression of HOXC8 is Associated With Poor Prognosis in Epithelial Ovarian Cancer
Shu-min Lu
,
Rong Liu
,
+10 authors
G. Mao
Reproductive Sciences
2016
Corpus ID: 19795374
Homeobox C8 (HOXC8) is a transcription factor that has been reported as a potential driver oncogene in several tumors and…
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Review
2014
Review
2014
Vertically integrated translational studies of PDX1 as a therapeutic target for pancreatic cancer via a novel bifunctional RNAi platform
J. Wu
,
S. Liu
,
+10 authors
F. Brunicardi
Cancer Gene Therapy
2014
Corpus ID: 7871615
RNA interference (RNAi) represents a powerful, new tool for scientific investigation as well as a promising new form of targeted…
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2012
2012
Effect of vitrification on promoter methylation and the expression of pluripotency and differentiation genes in mouse blastocysts
Xueming Zhao
,
W. Du
,
+4 authors
Huabin Zhu
Molecular Reproduction and Development
2012
Corpus ID: 25607412
The present study was designed to determine the effects of vitrification on promoter methylation and the expression levels of…
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2012
2012
HNF1B deficiency causes ciliary defects in human cholangiocytes
P. Roelandt
,
A. Antoniou
,
+10 authors
D. Cassiman
Hepatology
2012
Corpus ID: 6136643
Heterozygous deletion or mutation in hepatocyte nuclear factor 1 homeobox B/transcription factor 2 (HNF1B/TCF2) causes renal cyst…
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2012
2012
Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2 autism spectrum disorder-associated haplotype function.
Jiyeon Choi
,
Myka R. Ababon
,
P. Matteson
,
J. Millonig
Human Molecular Genetics
2012
Corpus ID: 13909619
Both common and rare variants contribute to autism spectrum disorder (ASD) risk, but few variants have been established as…
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2012
2012
Detection of IGF2BP3, HOXB7, and NEK2 mRNA Expression in Brush Cytology Specimens as a New Diagnostic Tool in Patients with Biliary Strictures
H. Nischalke
,
V. Schmitz
,
+6 authors
J. Nattermann
PLoS ONE
2012
Corpus ID: 6852784
Introduction It is a challenging task to distinguish between benign and malignant lesions in patients with biliary strictures…
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2010
2010
Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization
R. An
,
G. da Silva Xavier
,
+7 authors
G. Rutter
Biochemical and Biophysical Research…
2010
Corpus ID: 10672675
2006
2006
The PDX1 Homeodomain Transcription Factor Negatively Regulates the Pancreatic Ductal Cell-specific Keratin 19 Promoter*
T. Deramaudt
,
M. Sachdeva
,
Melanie P. Wescott
,
Yuting Chen
,
D. Stoffers
,
A. Rustgi
Journal of Biological Chemistry
2006
Corpus ID: 41501957
Keratin 19 is a member of the cytokeratin family that is critical for maintenance of cellular architecture and organization…
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2000
2000
Transforming growth factor beta induction of insulin gene expression is mediated by pancreatic and duodenal homeobox gene-1 in rat insulinoma cells.
Yoshitaka Sayo
,
H. Hosokawa
,
+5 authors
J. Takahara
European Journal of Biochemistry
2000
Corpus ID: 41350438
Although transforming growth factor-beta (TGF-beta) stimulates pancreatic islet cells to synthesize and secret insulin, the…
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1999
1999
Psx homeobox gene is X‐linked and specifically expressed in trophoblast cells of mouse placenta
J. Chun
,
Yun-Jeong Han
,
K. Ahn
Developmental Dynamics
1999
Corpus ID: 41448121
We previously isolated a cDNA clone for a homeobox‐containing gene with its expression restricted to the extraembryonic tissues…
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