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NHEJ1 gene

Known as: NEJ1, S. CEREVISIAE, HOMOLOG OF, XRCC4-LIKE FACTOR, FLJ12610 
This gene is involved in DNA repair and V(D)J recombination.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
A factor for repairing broken DNA Unprogrammed DNA double-strand breaks are extremely dangerous for genomic stability… Expand
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Review
2011
Review
2011
High-fidelity replication of DNA, and its accurate segregation to daughter cells, is critical for maintaining genome stability… Expand
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Highly Cited
2010
Highly Cited
2010
The repair of DNA double-strand breaks (DSBs) is critical for the maintenance of genomic integrity and viability for all… Expand
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Highly Cited
2009
Highly Cited
2009
XLF-Cernunnos (XLF) is a component of the DNA ligase IV–XRCC4 (LX) complex, which functions during DNA non-homologous end joining… Expand
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Highly Cited
2008
Highly Cited
2008
Mutations in XLF/Cernunnos (XLF) cause lymphocytopenia in humans, and various studies suggest an XLF role in classical… Expand
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Highly Cited
2008
Highly Cited
2008
XRCC4-like factor (XLF)--also known as Cernunnos--has recently been shown to be involved in non-homologous end-joining (NHEJ… Expand
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Highly Cited
2007
Highly Cited
2007
Nonhomologous end-joining (NHEJ) repairs DNA double-strand breaks created by ionizing radiation or V(D)J recombination of the… Expand
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Highly Cited
2006
Highly Cited
2006
Poly(ADP-ribose)polymerase 1 (PARP-1) recognizes DNA strand interruptions in vivo and triggers its own modification as well as… Expand
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Highly Cited
2006
Highly Cited
2006
DNA nonhomologous end-joining (NHEJ) is a predominant pathway of DNA double-strand break repair in mammalian cells, and defects… Expand
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Highly Cited
2006
Highly Cited
2006
DNA double-strand breaks (DSBs) occur at random upon genotoxic stresses and represent obligatory intermediates during… Expand
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