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NHEJ1 protein, human

Known as: XLF protein, human, XRCC4-Like Factor, FLJ12610 protein, human 
Non-homologous end-joining factor 1 (299 aa, ~33 kDa) is encoded by the human NHEJ1 gene. This protein is involved in both the repair of double… 
National Institutes of Health

Papers overview

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2019
2019
Chen et al. show that XLF functions to limit fork reversal during DNA replication. H2AX prevents MRE11-dependent replication… 
Highly Cited
2013
Highly Cited
2013
Ligase IV, but not its catalytic function, is required for DNA-PK–dependent end synapsis during nonhomologous end joining. 
2011
2011
B cell-negative severe combined immunodeficiency (SCID) is caused by molecules involved in the variable (diversity) joining (V[D… 
Highly Cited
2008
Highly Cited
2008
XLF-Cernunnos (XLF) is a component of the DNA ligase IV–XRCC4 (LX) complex, which functions during DNA non-homologous end joining… 
Review
2006
Review
2006
Purpose of review The analysis of immune deficiency conditions in humans has recently allowed the identification of a novel… 
Review
2006
Review
2006
BackgroundCernunnos-XLF is a nonhomologous end-joining factor that is mutated in patients with a rare immunodeficiency with… 
1995
1995
Oncogenic retroviruses carry coding sequences that are transduced from cellular protooncogenes. Natural transduction involves two…