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NFKB1 wt Allele

Known as: KBF1, NFKB-p105, MGC54151 
Human NFKB1 wild-type allele is located in the vicinity of 4q24 and is approximately 105 kb in length. This allele, which encodes nuclear factor NF… 
National Institutes of Health

Related topics

Related topics

21 relations
Adipocytokine Signaling PathwayApoptosisB Cell Receptor Signaling PathwayCeramide Signaling Pathway PID

Broader (1)

NFKB1 gene

Papers overview

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Highly Cited
2013
Highly Cited
2013
Dietary phytochemicals as potent chemotherapeutic agents against breast cancer: Inhibition of NF-κB pathway via molecular interactions in rel homology domain of its precursor protein p105
Background: Dietary phytochemicals consist of a wide variety of biologically active compounds that are ubiquitous in plants, many… 
Highly Cited
2006
Highly Cited
2006
Human Papillomavirus Type 16 E6 Activates NF-κB, Induces cIAP-2 Expression, and Protects against Apoptosis in a PDZ Binding Motif-Dependent Manner
ABSTRACT Infection with human papillomavirus (HPV) is a critical factor in the pathogenesis of most cervical cancers and some… 
Highly Cited
2004
Highly Cited
2004
NF-κB and p53 Are the Dominant Apoptosis-inducing Transcription Factors Elicited by the HIV-1 Envelope
The coculture of cells expressing the HIV-1 envelope glycoprotein complex (Env) with cells expressing CD4 results into cell… 
Highly Cited
1999
Highly Cited
1999
Induction of Bcl-xL Expression by Human T-Cell Leukemia Virus Type 1 Tax through NF-κB in Apoptosis-Resistant T-Cell Transfectants with Tax
ABSTRACT Human T-cell leukemia virus type 1 (HTLV-1) Tax is thought to play a pivotal role in immortalization of T cells. We have… 
Highly Cited
1998
Highly Cited
1998
Cotranslational Biogenesis of NF-κB p50 by the 26S Proteasome
Highly Cited
1993
Highly Cited
1993
KBF1 (p50 NF-kappa B homodimer) acts as a repressor of H-2Kb gene expression in metastatic tumor cells
Downregulation of major histocompatibility complex class I expression is causally related to high malignancy and low… 
Highly Cited
1992
Highly Cited
1992
Transcriptional activator Tax of HTLV-1 binds to the NF-kappa B precursor p105.
Human T-cell leukemia virus type 1 (HTLV-1) induces adult T-cell leukemia and also a neurological disease, tropical spastic… 
Highly Cited
1989
Highly Cited
1989
TNF stimulates expression of mouse MHC class I genes by inducing an NF kappa B‐like enhancer binding activity which displaces constitutive factors.
We have dissected the mouse H‐2Kb gene promoter in order to define the sequences responsible for induction by tumour necrosis… 
Highly Cited
1987
Highly Cited
1987
Purification of KBF1, a common factor binding to both H‐2 and beta 2‐microglobulin enhancers.
An enhancer binding factor, designated KBF1, has been purified from the nuclear extract of mouse BW5147 thymoma cells by five… 
Highly Cited
1987
Highly Cited
1987
Modulation of the nuclear antigen p105 as a function of cell‐cycle progression
The characterization of the proliferation‐associated nuclear antigen designated p105 in quiescent and proliferating lymphocytes… 
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