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NFAT5 protein, human

Known as: TonEBP, T-Cell Transcription Factor NFAT5, Nuclear Factor of Activated T-Cells 5 
Nuclear factor of activated T-cells 5 (1531 aa, ~166 kDa) is encoded by the human NFAT5 gene. This protein is involved in the modulation of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
There has been a marked increase in the incidence of autoimmune diseases in the past half-century. Although the underlying… Expand
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Highly Cited
2013
Highly Cited
2013
The skin interstitium sequesters excess Na+ and Cl- in salt-sensitive hypertension. Mononuclear phagocyte system (MPS) cells are… Expand
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Review
2012
Review
2012
Tonicity-responsive enhancer binding protein (TonEBP/nuclear factor of activated T-cells 5 [NFAT5]) is a Rel homology… Expand
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Highly Cited
2010
Highly Cited
2010
Tonicity responsive binding protein (TonEBP) is a transcription factor that plays a key role in osmoprotection. Here, we… Expand
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Review
2006
Review
2006
TonEBP stimulates genes whose products drive cellular accumulation of organic osmolytes and HSP70, which protect cells from the… Expand
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2006
2006
Glycerophosphocholine (GPC) is an osmoprotective compatible and counteracting organic osmolyte that accumulates in renal inner… Expand
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Review
2005
Review
2005
  • Dietmar Kültz
  • American journal of physiology. Renal physiology
  • 2005
  • Corpus ID: 7528430
osmotic stress occurs when the concentration of dissolved compounds in water surrounding cells and organisms changes. For example… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT While hyperosmolality of the kidney medulla is essential for urinary concentration, it imposes a great deal of stress… Expand
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Highly Cited
2002
Highly Cited
2002
When cells are challenged by hyperosmotic stress, one of the crucial adaptive responses is the expression of osmoprotective genes… Expand
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Highly Cited
2000
Highly Cited
2000
NFAT DNA binding complexes regulate programs of cellular activation and differentiation by translating receptor-dependent… Expand
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