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NEDD4 gene

Known as: NEDD4-1, Neural Precursor Cell Expressed, Developmentally Down-Regulated 4, E3 Ubiquitin Protein Ligase Gene, RPF1 
This gene may play a role in viral infection and tumor suppression.
National Institutes of Health

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E3 Ubiquitin-Protein Ligase NEDD4, HumanUbiquitination

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NEDD4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
LSC - 2019 - Development of pulmonary fibrosis in conditional Nedd4-2 deficient mice
2013
2013
Abstract 4281: Nedd4 controls cell migration by regulating PDGF receptor signaling.
The ubiquitin ligase Nedd4 is an ubuiquitin ligase (E3) which belongs to the HECT family. Like other member of this family… 
2013
2013
4-2 Protein Channel Surface Expression by Inhibiting Kinase 1 ( SGK 1 ) Pathway Promotes Kv 7 . 1 glucocorticoid-inducible ( PI 3 K )-serum-and A Phosphoinositide 3-Kinase Cell Biology :
2012
2012
Abstract LB-280: RNP biogenesis factor Thoc1 is targeted for ubiquitination by NEDD4-1 E3 ligase
Thoc1 encodes an essential protein component (pThoc1) of the THO complex that regulates the packaging of nascent transcripts into… 
2011
2011
Cationic Amino Acid Transporter CAT-1 and Clathrin-mediated Endocytosis of the Protein Kinase C-dependent Ubiquitination Membrane Biology :
2010
2010
, Response to Zinc Ligase NEDD 4-1 during Neuronal Tensin Homologue ( PTEN ) with the E 3 Functional Interaction of Phosphatase and Neurobiology
2010
2010
Tumorigenesis and Neoplastic Progression Oncogenic Role of the E 3 Ubiquitin Ligase NEDD 4-1 , a PTEN Negative Regulator , in Non-Small-Cell Lung Carcinomas
Loss of the PTEN tumor suppressor gene occurs frequently in non-small-cell lung carcinoma (NSCLC), although neither genetic… 
2010
2010
COMMD 1 downregulates the epithelial sodium channel through Nedd 4 – 2
Ke Y, Butt AG, Swart M, Liu YF, McDonald FJ. COMMD1 downregulates the epithelial sodium channel through Nedd4–2. Am J Physiol… 
2008
2008
Response Activity and Enhances the Innate Antiviral ISG 15 Inhibits Nedd 4 Ubiquitin E 3 Accelerated
2008
2008
Herpes simplex virus type 2 UL56 interacts with the ubiquitin ligase Nedd4 and increases its ubiquitination