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E3 Ubiquitin-Protein Ligase NEDD4, Human

Known as: E3 Ubiquitin-Protein Ligase NEDD4, Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 4, Receptor-Potentiating Factor 1 
E3 ubiquitin-protein ligase NEDD4 (1000 aa, ~115 kDa) is encoded by the human NEDD4 gene. This protein is involved in the transfer of ubiquitin to… Expand
National Institutes of Health

Papers overview

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2017
2017
&NA; Pancreatic cancer (PC) is one of the most fatal cancers worldwide. The incidence and death rates are still increasing for PC… Expand
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2017
2017
ABSTRACT The neural precursor cell expressed developmentally downregulated protein 4 (NEDD4) plays a pivotal oncogenic role in… Expand
2016
2016
Peroxisome proliferator–activated receptor-γ (PPARγ) is a ligand-activated nuclear receptor which controls lipid and glucose… Expand
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Highly Cited
2016
Highly Cited
2016
Significance The voltage-gated sodium channel NaV1.7 is important for electrogenesis in sensory neurons. Insertion within the… Expand
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Highly Cited
2015
Highly Cited
2015
Inhibition of placental mechanistic target of rapamycin (mTOR) signalling, which activates NEDD4-2 (neural precursor cell… Expand
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2015
2015
Nedd4 (neural precursor cell expressed developmentally down‐regulated protein 4) is a member of the HECT E3 ubiquitin ligases… Expand
2014
2014
Background: Nedd4-1 catalyzes the Lys-63-linked ubiquitination of aS. Results: The Lys-63-linked ubiquitination of aS by Nedd4-1… Expand
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2014
2014
CD40, a member of tumour necrosis factor receptor (TNFR) superfamily, has a pivotal role in B-cell-mediated immunity through… Expand
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2012
2012
Kif26b, a member of the kinesin superfamily proteins (KIFs), is essential for kidney development. Kif26b expression is restricted… Expand
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Highly Cited
1997
Highly Cited
1997
In most instances, the transfer of ubiquitin to target proteins is catalyzed by the action of ubiquitin protein ligases (E3s… Expand
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