E3 Ubiquitin-Protein Ligase NEDD4, Human
Semantic Scholar uses AI to extract papers important to this topic.
&NA; Pancreatic cancer (PC) is one of the most fatal cancers worldwide. The incidence and death rates are still increasing for PC… Expand ABSTRACT The neural precursor cell expressed developmentally downregulated protein 4 (NEDD4) plays a pivotal oncogenic role in… Expand Peroxisome proliferator–activated receptor-γ (PPARγ) is a ligand-activated nuclear receptor which controls lipid and glucose… Expand Significance The voltage-gated sodium channel NaV1.7 is important for electrogenesis in sensory neurons. Insertion within the… Expand Inhibition of placental mechanistic target of rapamycin (mTOR) signalling, which activates NEDD4-2 (neural precursor cell… Expand Nedd4 (neural precursor cell expressed developmentally down‐regulated protein 4) is a member of the HECT E3 ubiquitin ligases… Expand Background: Nedd4-1 catalyzes the Lys-63-linked ubiquitination of aS. Results: The Lys-63-linked ubiquitination of aS by Nedd4-1… Expand CD40, a member of tumour necrosis factor receptor (TNFR) superfamily, has a pivotal role in B-cell-mediated immunity through… Expand Kif26b, a member of the kinesin superfamily proteins (KIFs), is essential for kidney development. Kif26b expression is restricted… Expand In most instances, the transfer of ubiquitin to target proteins is catalyzed by the action of ubiquitin protein ligases (E3s… Expand