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NCOA2 wt Allele

Known as: GRIP1, Nuclear Receptor Coactivator 2 wt Allele, TIF2 
Human NCOA2 wild-type allele is located in the vicinity of 8q13.2 and is approximately 292 kb in length. This allele, which encodes nuclear receptor… 
National Institutes of Health

Related topics

Related topics

14 relations
8q13.1Androgen Receptor Regulation PathwayCell Differentiation processCell Fate Control

Broader (1)

NCOA2 gene

Papers overview

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2005
2005
Role of activation function domain-1, DNA binding, and coactivator GRIP1 in the expression of partial agonist activity of glucocorticoid receptor-antagonist complexes.
The determinants of the partial agonist activity of most antisteroids complexed with steroid receptors are not well understood… 
2005
2005
Mouse estrogen receptor beta isoforms exhibit differences in ligand selectivity and coactivator recruitment.
Estrogens exert their physiological effects through two estrogen receptor (ER) subtypes, ERalpha and ERbeta. In mouse, the… 
Highly Cited
2004
Highly Cited
2004
Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction.
Both SRC-1 and TIF2 are members of the p160 steroid receptor coactivator family. Genetic analyses have shown that inactivation of… 
Highly Cited
2004
Highly Cited
2004
Differential modulation of androgen receptor transcriptional activity by the nuclear receptor co-repressor (N-CoR).
Antiandrogens are widely used agents in the treatment of prostate cancer, as inhibitors of AR (androgen receptor) action… 
2004
2004
The genes of the coactivator TIF2 and the corepressor SMRT are primary 1α,25(OH)2D3 targets
2003
2003
Molecular Determinants of the Stereoselectivity of Agonist Activity of Estrogen Receptors (ER) α and β*
The two known estrogen receptors, ERα and ERβ, are hormone-inducible transcription factors that have distinct roles in regulating… 
Highly Cited
2002
Highly Cited
2002
Androgen Receptor-interacting Protein 3 and Other PIAS Proteins Cooperate with Glucocorticoid Receptor-interacting Protein 1 in Steroid Receptor-dependent Signaling*
Androgen receptor (AR)-interacting protein 3 (ARIP3/PIASxα) is a coregulator capable of modulating transcriptional activity of… 
2002
2002
Regulation of GRIP1 and CBP Coactivator Activity by Rho GDI Modulates Estrogen Receptor Transcriptional Enhancement*
Estrogen receptor α (ER) coordinates gene expression with cellular physiology in part by controlling receptor- cofactor… 
Highly Cited
1999
Highly Cited
1999
An Additional Region of Coactivator GRIP1 Required for Interaction with the Hormone-binding Domains of a Subset of Nuclear Receptors*
Transcriptional coactivators of the p160 family (SRC-1, GRIP1, and p/CIP) associate with DNA-bound nuclear receptors (NRs) and… 
Highly Cited
1997
Highly Cited
1997
Yeast hormone response element assays detect and characterize GRIP1 coactivator-dependent activation of transcription by thyroid and retinoid nuclear receptors.
The mouse glucocorticoid receptor-interacting protein (GRIP1) is a member of the ERAP160 family of nuclear receptor (NR… 
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