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NCF2 gene

Known as: NCF2, p67-PHOX, Neutrophil Cytosolic Factor 2 Gene 
This gene plays a role in the generation of superoxide in neutrophils.
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Systemic lupus erythematosus (SLE), the prototypic systemic autoimmune disease, is a debilitating multisystem autoimmune disorder… Expand
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Highly Cited
2011
Highly Cited
2011
Objective The NOX2 NADPH oxidase complex produces reactive oxygen species and plays a critical role in the killing of microbes by… Expand
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Highly Cited
2002
Highly Cited
2002
Phagocytes generate superoxide anion (O2−) by a classic, 5-component NADPH oxidase. O2− contributes to hypertension in… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND & AIMS Superoxide anion (O2-) plays an important role in gastric pathophysiology. The aims of this study were to… Expand
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Highly Cited
1994
Highly Cited
1994
Src homology 3 (SH3) domains have been suggested to play an important role in the assembly of the superoxide-forming nicotinamide… Expand
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Highly Cited
1994
Highly Cited
1994
NADPH-dependent superoxide generation was activated by anionic amphiphiles plus GTP gamma S in a cell-free system consisting of… Expand
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Highly Cited
1992
Highly Cited
1992
Activation of the NADPH oxidase of phagocytes in the cell-free system requires the association of several cytosolic components… Expand
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Highly Cited
1992
Highly Cited
1992
The superoxide-generating NADPH oxidase system in phagocytes consists of at least membrane-associated cytochrome b558 and three… Expand
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Highly Cited
1991
Highly Cited
1991
Two of the cytosolic NADPH oxidase components, p47-phox and p67-phox, translocate to the plasma membrane in normal neutrophils… Expand
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Highly Cited
1991
Highly Cited
1991
Superoxide production by phagocytic blood cells involves assembly of an active NADPH oxidase complex from components found both… Expand
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