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NCF2 gene

Known as: NCF2, p67-PHOX, Neutrophil Cytosolic Factor 2 Gene 
This gene plays a role in the generation of superoxide in neutrophils.
National Institutes of Health

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Related topics

7 relations
Antigen PresentationAntigen ProcessingImmune System ProcessesNCF4 gene

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NCF2 wt Allele

Papers overview

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2008
2008
Characterization of teleost phagocyte NADPH oxidase: molecular cloning and expression analysis of carp (Cyprinus carpio) phagocyte NADPH oxidase.
2001
2001
H2O2-Forming NADH Oxidase with Diaphorase (Cytochrome) Activity from Archaeoglobus fulgidus
ABSTRACT An enzyme exhibiting NADH oxidase (diaphorase) activity was isolated from the hyperthermophilic sulfate-reducing… 
1996
1996
Neutrophils from patients after burn injury express a deficiency of the oxidase components p47-phox and p67-phox.
Infection is a major cause of morbidity and mortality in patients after thermal injury. This predisposition to infections is… 
1996
1996
Neutrophils from patients after burn injury express a deficiency of the oxidase components p47-phox and p67-phox
Infection is a major cause of morbidity and mortality in patients after thermal injury. This predisposition to infections is… 
Review
1995
Review
1995
Mapping the Domains of Interaction of p40 with Both p47 and p67 of the Neutrophil Oxidase Complex Using the Two-hybrid System (*)
The superoxide-generating NADPH oxidase complex in phagocytic cells is constituted of a heterodimeric flavocytochrome b and… 
1994
1994
Expression of p47‐phox and p67‐phox proteins in murine bone marrow–derived macrophages: Enhancement by lipopolysaccharide and tumor necrosis factor α but not colony stimulating factor 1
We have investigated the relationship between the expression of the p47‐phox and p67‐phox cytosolic components of the NADPH… 
1993
1993
The respiratory burst oxidase of human neutrophils. Guanine nucleotides and arachidonate regulate the assembly of a multicomponent complex in a semirecombinant cell-free system.
Highly Cited
1992
Highly Cited
1992
Regulation of the superoxide-generating NADPH oxidase by a small GTP-binding protein and its stimulatory and inhibitory GDP/GTP exchange proteins.
1992
1992
Reconstitution and characterization of the human neutrophil respiratory burst oxidase using recombinant p47-phox, p67-phox and plasma membrane.
1992
1992
Identification of a thermolabile component of the human neutrophil NADPH oxidase. A model for chronic granulomatous disease caused by deficiency of the p67-phox cytosolic component.
Mild heating of human neutrophils inactivates the respiratory burst oxidase, producing a defect in superoxide production and… 
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